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2020, vol. 73, br. 11-12, str. 357-363
Neurokognitivne promene kod onkoloških pacijenata kao aktuelni izazov u psihoonkologiji
aUniverzitet u Novom Sadu, Medicinski fakultet, Srbija + Institut za onkologiju Vojvodine, Sremska Kamenica, Srbija
bUniverzitet u Novom Sadu, Medicinski fakultet, Srbija + Klinički centar Vojvodine, Klinika za neurologiju, Novi Sad, Srbija
cUniverzitet u Novom Sadu, Filozofski fakultet, Odsek za psihologiju, Srbija
dUniversity of Novi Sad, Faculty of Medicine Novi Sad, Department of Radiology, Novi Sad + Institut za onkologiju Vojvodine, Sremska Kamenica, Srbija

e-adresaaleksandra.kovac@mf.uns.ac.rs
Ključne reči: neurokognitivni poremećaji; onkološki bolesnici; psiho-onkologija; neuropsihologija; neuroimidžing; kognitivni poremećaji; afektivni simptomi; kognitivni poremećaji uzrokovani hemoterapijom; psihološki poremećaj; ličnost
Sažetak
Uvod. Uz visok intenzitet emocionalnog distresa, onkološki pacijenti često se suočavaju sa neurokognitivnim promenama koje postaju naročito izražene nakon hemioterapije. Kliničke manifestacije neurokognitivnog deficita kod pacijenata koji nemaju tumor centralnog nervnog sistema. Dosadašnje studije su pokazale da se kognitivne smetnje najčešće javljaju u domenima egzekutivnih funkcija, pažnje i koncentracije, radne memorije, brzine procesiranja informacija i vizuospacijalnih sposobnosti, te za iste još uvek ne postoji krajnje definisan protokol dijagnostike i lečenja. Potencijalni etiološki mehanizmi i faktori rizika. Pored hemioterapije, važnu ulogu u nastanku i manifestaciji neurokognitivnog deficita kod onkoloških pacijenata imaju i drugi: genetski, biološki, psihološki i sociodemografski faktori. Metode procene neurokognitivnog deficita kod onkoloških pacijenata. Za procenu eventualnog neurokognitivnog oštećenja najbolje je koristiti kombinaciju koja uključuje neuropsihološku dijagnostiku i inventare za samoprocenu kognitivnog i afektivnog statusa, kao i savremene metode neuroimidžing dijagnostike koje će ukazati na neuralne (strukturalne i funkcionalne) promene koje leže u osnovi neurokognitivnog deficita. Uloga psihosocijalnih faktora - smernice za buduća istraživanja. Pored kognitivne rezerve i afektivnog statusa, potencijalnu ulogu u objašnjenju neurokognitivnog funkcionisanja i neurokognitivne adaptacije po završenom lečenju vrlo verovatno mogu imati i karakteristike ličnosti obolelih. Zaključak. Neophodne su nove studije koje će omogućiti dalje rasvetljavanje mehanizama koji leže u osnovi neurokognitivnih promena kod onkoloških pacijenata, sa posebnim akcentom na doprinos psihosocijalnih faktora, a na osnovu kojih će dalje biti omogućen i adekvatan i pravovremeni kognitivno-rehabilitacioni tretman obolelih od malignih bolesti.
Reference
Ahles, T.A., Saykin, A.J., Noll, W.W., Furstenberg, C.T., Guerin, S., Cole, B., et al. (2003) The relationship of APOE genotype to neuropsychological performance in long-term cancer survivors treated with standard dose chemotherapy. Psychooncology, 12(6): 612-9
Ahles, T.A., Saykin, A.J., McDonald, B.C., Li, Y., Furstenberg, C.T., Hanscom, B.S., Mulrooney, T.J., Schwartz, G.N., Kaufman, P.A. (2010) Longitudinal assessment of cognitive changes associated with adjuvant treatment for breast cancer: Impact of age and cognitive reserve. Journal of Clinical Oncology, 28(29): 4434-4440
Ahles, T.A., Saykin, A.J., Furstenberg, C.T., Cole, B., Mott, L.A., Skalla, K., Whedon, M.B., Bivens, S., Mitchell, T., Greenberg, E., Silberfarb, P.M. (2002) Neuropsychologic impact of standard-dose systemic chemotherapy in long-term survivors of breast cancer and lymphoma. Journal of Clinical Oncology, 20(2): 485-493
Andres, A.L., Gong, X., di Kaijun,, Bota, D.A. (2014) Low-doses of cisplatin injure hippocampal synapses: A mechanism for 'chemo' brain?. Experimental Neurology, 255: 137-144
Arnsten, A.F. (2015) Stress weakens prefrontal networks: Molecular insults to higher cognition. Nat Neurosci, 18(10): 1376-85
Asher, A., Myers, J.S. (2015) The effect of cancer treatment on cognitive function. Clin Adv Hematol Oncol, 13(7): 441-50
Boban, J., Trifunović, J., Kovač, A., Kozić, D. (2019) Chemobrain - uloga magnetnorezonantne volumetrije u detekciji promena nakon citostatske terapije karcinoma dojke. u: Drugi srpski senološki kongres: zbornik sažetaka; 2019 maj 24-25; Novi Sad, Srbija, Novi Sad: Senološko Udruženje Srbije, 40-40
Bugarski-Ignjatović, V., Kovač, A., Smederevac, S., Tovilović, S., Trifunović, J. (2019) Personality traits and executive functions in breast cancer patients. u: Popov B. [ur.] Current trends in psychology: book of abstracts; Oct 24-27; Novi Sad, Serbia, Faculty of Philosophy, 204-6
Chen, B.T., Ye, N., Wong, C.W., Patel, S.K., Jin, T., Sun, C.L., et al. (2020) Effects of chemotherapy on aging white matter microstructure: A longitudinal diffusion tensor imaging study. J Geriatr Oncol, 11(2):290-6
Cheung, Y.T., Shwe, M., Chui, W.K., Chay, W.Y., Ang, S.F., Dent, R.A., et al. (2012) Effects of chemotherapy and psychosocial distress on perceived cognitive disturbances in Asian breast cancer patients. Ann Pharmacother, 46(12): 1645-55
Conroy, S.K., McDonald, B.C., Smith, D.J., Moser, L.R., West, J.D., Kamendulis, L.M., et al. (2013) Alterations in brain structure and function in breast cancer survivors: Effect of post-chemotherapy interval and relation to oxidative DNA damage. Breast Cancer Res Treat, 137(2):493-502
de Ruiter, M.B., Reneman, L., Boogerd, W., Veltman, D.J., Caan, M., Douaud, G. (2012) Late effects of high-dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: Converging results from multimodal magnetic resonance imaging. Hum Brain Mapp, 33(12): 2971-83
Floyd, R., Dyer, A.H., Kennelly, S.P. (In press) Non-pharmacological interventions for cognitive impairment in women with breast cancer post-chemotherapy: A systematic review. J Geriatr Oncol
Franchow, E.I., Suchy, Y., Thorgusen, S.R., Williams, P. (2013) More than education: Openness to experience contributes to cognitive reserve in older adulthood. J Aging Sci, 1(2): 1-8
Hackman, D.A., Farah, M.J., Meaney, M.J. (2010) Socioeconomic status and the brain: Mechanistic insights from human and animal research. Nature Reviews Neuroscience, 11(9): 651-659
Joyner, C., Rhodes, R.E., Loprinzi, P.D. (2018) The prospective association between the five factor personality model with health behaviors and health behavior clusters. Eur J Psychol, 14(4): 880-96
Kabbara, A., Paban, V., Weill, A., Modolo, J., Hassan, M. (2020) Brain network dynamics correlate with personality traits. Brain Connect, 10(3): 108-20
Kartschmit, N., Mikolajczyk, R., Schubert, T., Lacruz, M.E. (2016) Measuring cognitive reserve (CR): A systematic review of measurement properties of CR questionnaires for the adult population. PLoS One, 14(8): e0219851-e0219851
Kaser, M., Zaman, R., Sahakian, B.J. (2017) Cognition as a treatment target in depression. Psychol Med, 47(6): 987-9
Kesler, S., Janelsins, M., Koovakkattu, D., Palesh, O., Mustian, K., Morrow, G., et al. (2013) Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors. Brain Behav Immun, 30(Suppl 0): S109-16
Kesler, S.R., Kent, J.S., O'Hara, R. (2011) Prefrontal cortex and executive function impairments in primary breast cancer. Archives of Neurology, 68(11): 1447-1453
Kesler, S.R., Blayney, D.W. (2016) Neurotoxic effects of anthracycline-vs nonanthracycline-based chemotherapy on cognition in breast cancer survivors. JAMA Oncol, 2(2): 185-92
Kesler, S.R., Watson, C., Koovakkattu, D., Lee, C., O'Hara, R., Mahaffey, M.L., Wefel, J.S. (2013) Elevated prefrontal myo-inositol and choline following breast cancer chemotherapy. Brain Imaging and Behavior, 7(4): 501-510
Koppelmans, V., Breteler, M.M., Boogerd, W., Seynaeve, C., Gundy, C., Schagen, S.B. (2012) Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy. J Clin Oncol, 30(10): 1080-6
Kovač, A., Bugarski-Ignjatović, V., Tovilović, S., Kozić, D., Trifunović, J., Popović-Petrović, S., et al. (2018) The impact of negative affect and emotional distress on executive functions in breast cancer patients. u: 1st PSU-UNS joint conference on medical science and technology: book of abstracts; 2018 Mar 5-7; Krabi, Thailand, Hat Yai District: Faculty of Medicine, 101-2
Kovač, A., Tovilović, S., Bugarski-Ignjatović, V., Popović-Petrović, S., Tatić, M. (2020) The role of cognitive emotion regulation strategies in health related quality of life of breast cancer patients. Vojnosanitetski pregled, vol. 77, br. 10, str. 1032-1040
Kovač, A., Popović-Petrović, S., Nedeljković, M., Kojić, M., Tomić, S. (2014) Post-operative condition of breast cancer patients from standpoint of psycho-oncology: Preliminary results. Medicinski pregled, 67(1-2): 43-8
Lange, M., Joly, F., Vardy, J., Ahles, T., Dubois, M., Tron, L., et al. (2019) Cancer-related cognitive impairment: An update on state of the art, detection, and management strategies in cancer survivors. Ann Oncol, 30(12): 1925-40
Lange, M., Rigal, O., Clarisse, B., Giffard, B., Sevin, E.B., Barillet, M., Eustache, F., Joly, F. (2014) Cognitive dysfunctions in elderly cancer patients: A new challenge for oncologists. Cancer Treatment Reviews, 40(6): 810-817
Libert, Y., Dubruille, S., Borghgraef, C., Etienne, A.M., Merckaert, I., Paesmans, M., Reynaert, C., Roos, M., Slachmuylder, J., Vandenbossche, S., Bron, D., Razavi, D. (2016) Vulnerabilities in older patients when cancer treatment is initiated: Does a cognitive Impairment impact the two-year survival?. PLoS One, 11(8): e0159734-e0159734
Lucassen, P.J., Oomen, C.A. (2016) Stress, hippocampal neurogenesis and cognition: Functional correlations. Front Biol (Beijing), 11(3): 182-92
Lukasik, K.M., Waris, O., Soveri, A., Lehtonen, M., Laine, M. (2019) The relationship of anxiety and stress with working memory performance in a large non-depressed sample. Front Psychol, 10: 4-4
M.Tucker, A., Stern, Y. (2011) Cognitive reserve in aging. Current Alzheimer Research, 8(4): 354-360
Macía, P., Gorbeña, S., Gómez, A., Barranco, M., Iraurgi, I. (2020) Role of neuroticism and extraversion in the emotional health of people with cancer. Heliyon, 6(7): e04281-e04281
Mandelblatt, J.S., Hurria, A., McDonald, B.C., Saykin, A.J., Stern, R.A., Vanmeter, J.W., et al. (2013) Cognitive effects of cancer and its treatments at the intersection of aging: what do we know: What do we need to know?. Semin Oncol, 40(6):709-25
McDonald, B.C., Conroy, S.K., Smith, D.J., West, J.D., Saykin, A.J. (2013) Frontal gray matter reduction after breast cancer chemotherapy and association with executive symptoms: A replication and extension study. Brain Behav Immun, 30(Suppl 0): S117-25
Miao, H., Li, J., Hu, S., He, X., Partridge, S.C., Ren, J., et al. (2016) Longterm cognitive impairment of breast cancer patients after chemotherapy: A functional MRI study. Eur J Radiol, 85(6): 1053-7
Ng, T., Teo, S.M., Yeo, H.L., Shwe, M., Gan, Y.X., Cheung, Y.T., Foo, K.M., Cham, M.T., Lee, J.A., Tan, Y.P., Fan, G., Yong, W.S., Preetha, M., Loh, W.K., Koo, S., Jain, A., Lee, G.E., Wong, M. (2016) Brain-derived neurotrophic factor genetic polymorphism (rs6265) is protective against chemotherapy-associated cognitive impairment in patients with early-stage breast cancer. Neuro-Oncology, 18(2): 244-251
Popović-Petrović, S., Kovač, A., Kovač, N., Tovilović, S., Novakov, I., Ćulibrk, D. (2018) Secondary lymphedema of the arm, the perception of the disease, self-efficacy and depression as determinants of quality of life in patients with breast cancer. Vojnosanitetski pregled, 75(10): 961-7
Roth, R.M., Isquith, P.K., Gioia, G.A. (2005) BRIEF-A: Behavior rating inventory of executive function: Adult version. Lutz: Psychological Assessment Resources
Simard, M., Hudon, C., van Reekum, R. (2009) Psychological distress and risk for dementia. Curr Psychiatry Rep, 11(1): 41-7
Small, B.J., Rawson, K.S., Walsh, E., Jim, H.S.L., Hughes, T.F., Iser, L., Andrykowski, M.A., Jacobsen, P.B. (2011) Catechol-O-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors. Cancer, 117(7): 1369-1376
Stern, Y., Barnes, C.A., Grady, C., Jones, R.N., Raz, N. (2019) Brain reserve, cognitive reserve, compensation, and maintenance: Operationalization, validity, and mechanisms of cognitive resilience. Neurobiol Aging, 83:124-9
Stouten-Kemperman, M.M., de Ruiter, M.B., Koppelmans, V., Boogerd, W., Reneman, L., Schagen, S.B. (2015) Neurotoxicity in breast cancer survivors ≥10 years post-treatment is dependent on treatment type. Brain Imaging and Behavior, 9(2): 275-84
Sutin, A.R., Stephan, Y., Luchetti, M., Terracciano, A. (2019) Fivefactor model personality traits and cognitive function in five domains in older adulthood. BMC Geriatr, 19(1): 343-343
Terracciano, A., Stephan, Y., Luchetti, M., Albanese, E., Sutin, A.R. (2017) Personality traits and risk of cognitive impairment and dementia. Journal of Psychiatric Research, 89: 22-27
Wang, X.M., Walitt, B., Saligan, L., Tiwari, A.F., Cheung, C.W., Zhang, Z.J. (2015) Chemobrain: A critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy. Cytokine, 72(1): 86-96
Wefel, J.S., Saleeba, A.K., Buzdar, A.U., Meyers, C.A. (2010) Acute and late onset cognitive dysfunction associated with chemotherapy in women with breast cancer. Cancer, 116(14): 3348-56
Wefel, J.S., Vardy, J., Ahles, T., Schagen, S.B. (2011) International Cognition and Cancer Task Force recommendations to harmonise studies of cognitive function in patients with cancer. Lancet Oncology, 12(7): 703-708
Wigmore, P. (2013) The effect of systemic chemotherapy on neurogenesis, plasticity and memory. Curr Top Behav Neurosci, 15: 211-40
 

O članku

jezik rada: engleski
vrsta rada: pregledni članak
DOI: 10.2298/MPNS2012357K
primljen: 18.12.2020.
revidiran: 31.12.2020.
prihvaćen: 01.02.2021.
objavljen u SCIndeksu: 06.08.2022.

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