Article metrics

  • citations in SCindeks: [1]
  • citations in CrossRef:[1]
  • citations in Google Scholar:[=>]
  • visits in previous 30 days:6
  • full-text downloads in 30 days:6
article: 8 from 31  
Back back to result list
Praxis medica
2015, vol. 44, iss. 2, pp. 75-81
article language: Serbian
document type: Review Paper
published on: 30/08/2015
doi: 10.5937/pramed1502075S
The cultural and medical determination of the obesity
University of Kragujevac, Faculty of Medicine



Modern aspects of social development brings new concerns that contribute to obesity, as a direct result of the overall abundance. Almost that there is declarative consistent view that obesity, according to its frequency, a global epidemic of the new millennium and that is because of the effect on the overall health of the necessary complementary multidisciplinary approach, because its prevention can prevent and significantly reduce the mortality rate. Technological development, automation in the food production, reduced participation of manual labor and a sedentary lifestyle, obesity causes an increase not only in highly industrialized, but in the less developed countries. Obesity is a direct temptations of modern civilization and a major challenge for a community where food is plentiful. This fact increases the responsibility of each individual and placed before him the obligation to recognize the causes of obesity, so that, by changing their behavior, could reduce the burden involved with obesity.



Ahima, R.S. (2008) Revisiting leptin's role in obesity and weight loss. J Clin Invest, 118, (7), 2380-83
Atkinson, R.L. (2007) Viruses as an etiology of obesity. Mayo Clinic Proceedings, Oct., vol. 82 br. 10 1192-1198
Belluscio, D.O. The worldwide obesity epidemic.
Cejas, P., Casado, E., Belda-Iniesta, C., i dr. (2004) Implications of oxidative stress and cell membrane lipid peroxidation in human cancer (spain). Cancer Causes and Control, 15 (7): 707
Chan, J.L., Heist, K., DePaoli, A.M., Veldhuis, J.D., Mantzoros, C.S. (2003) The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. Journal of Clinical Investigation, 111(9): 1409-1421
Christiakis, N.A., Fowler, J.H. (2007) The spread of obesity in a large social network over 32 years. NEJM, 4, 357-79
Department of health and human services Centers for diseases control and prevention: Overweight and obesity.
Faith, M.S., Matz, P.E., Jorge, M.A. (2002) Obesity-depression associations in the population. Journal of psychosomatic research / J Psychosom Res, 53(4): 935-42
Flegal, K.M., Tabak, C.J., Ogden, C.L. (2006) Overweight in children: Definitions and interpretation. Health Education Research, 21(6): 755
Frankel, D.S., Vasan, R.S., D`Agostino, R.B., Benjamin, E.J., Levy, D., Wang, T.J., Meigs, J.B. (2009) Resistin, adiponectin, and risk of heart failure the Framingham offspring study. Journal of the American College of Cardiology, 53(9): 754-62
Goldstein, B.J., Ahmad, F., Ding, W., Li, P., Zhang, W. (1998) Regulation of the insulin signalling pathway by cellular protein-tyrosine phosphatases. Mol Cell Biochem, 182: 91-9
Gregory, E.S., Arterburn, D., Rohde, P., Ludman, E.J., Linde, J.A., Operskalski, B.H., i dr. (2011) Obesity, depression, and health services costs among middle-aged women. J Gen Intern Med., DOI: 10.1007/s11606-011-1774-x
Grundy, S.M. (2004) Obesity, Metabolic Syndrome, and Cardiovascular Disease. Journal of Clinical Endocrinology & Metabolism, 89(6): 2595-2600
Hedley, A.A., Ogden, C.L., Johnson, C.L., Carroll, M.D., Curtin, L.R., Flegal, K.M. (2004) Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA, 291(23): 2847-50
Hjemdahl, P. (2002) Stress and the Metabolic Syndrome: An Interesting but Enigmatic Association. Circulation, 106(21): 2634-2636
Hopkins, T., Ouchi, N., Shibata, R., Walsh, K. (2007) Adiponectin actions in the cardiovascular system. Cardiovascular Research, 74(1): 11-18
Hu, F.B. (2008) Obesity epidemiology. NEJM, 359, 1299-00
Inadera, H. (2008) The usefulness of circulating adipokine levels for the assessment of obesity-related health problems. International journal of medical sciences, 5(5): 248-62
Janovski, S.Z., Janovski, J.A. (2002) Obesity. NEJM, 346, 591-02
Jovanović, A., Marković-Jovanović, S. (2010) Dijabetes melitus tip 2 kao komplikacija gojaznosti. in: Stolić R. [ed.] Komorbiditeti gojaznosti i neka odabrana poglavlja, K. Mitrovica, str: 142-153
Kim, Y., Nikoulina, S.E., Ciaraldi, T.P., Henry, R.R., Kahn, B.B. (1999) Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes. Journal of Clinical Investigation, 104(6): 733-741
Korner, J., Leibel, R.L. (2003) To Eat or Not to Eat — How the Gut Talks to the Brain. New England Journal of Medicine, 349(10): 926-928
Lundberg, U., John, D. (2003) Research network on socioeconomic status and health: Catecholamines and environmental stress. September,, Department of Psychology, Stockholm University for the Allostatic Load Notebook, CT Mac Arthur
Marčetić, Z. (2010) Gojaznost, arterijska hipertenzija i ishemijska bolest srca. in: Stolić R. [ed.] Komorbiditeti gojaznosti i neka odabrana poglavlja, K. Mitrovica, str: 84-97
Norata, G.D., Ongari, M., Garlaschelli, K., Raselli, S., Grigore, L., Catapano, A.L. (2007) Plasma resistin levels correlate with determinants of the metabolic syndrome. European journal of endocrinology, 156(2): 279-84
Ogden, C.L., Caroll, M.D., Flegal, K.M. (2008) High body mas s index for age among US children and adolescents 2003-2006. JAMA, 299, str. 2401-2405
Onyike, C.U., Crum, R.M., Lee, H.B., Lyketsos, C.G., Eaton, W.W. (2003) Is obesity associated with major depression? Results from the Third National Health and Nutrition Examination Survey. Am J Epidemiol, 158(12): 1139-47
Packard, R.R.S., Libby, P. (2008) Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clinical chemistry, 54(1): 24-38
Racette, S.B., Deusinger, S.S., Deusinger, R.H. (2003) Obesity: Overview of prevalence, etiology, and treatment. PHYS THER., 83, 276-88
Rašić, D., Stolić, R., Jovanović, A., Trajković, G., Rašić, J., Sovtić, S. (2010) The significance of resistin concentration in metabolical diseases. Vojnosanitetski pregled, vol. 67, br. 12, str. 965-968
Reaven, G.M. (1995) Pathophysiology of insulin resistance in human disease. Physiol Rev, 75(3): 473-86
Rosenbaum, M. (2005) Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight. Journal of Clinical Investigation, 115(12): 3579-3586
Rosenbaum, M., Sy, M., Pavlovich, K., Leibel, R.L., Hirsch, J. (2008) Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli. J Clin Invest, 118, (7), 2583-91
Sachdev, D., Yee, D. (2007) Disrupting insulin-like growth factor signaling as a potential cancer therapy. Molecular Cancer Therapeutics, 6(1): 1-12
Segerstrom, S.C., Miller, G.E. (2004) Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry. Psychological bulletin, 130(4): 601-30
Segura, J., Campo, C., Roldán, C., Christiansen, H., Vigil, L., García-Robles, R., Rodicio, J.L., Ruilope, L.M. (2004) Hypertensive renal damage in metabolic syndrome is associated with glucose metabolism disturbances. J Am Soc Nephrol, 15 Suppl 1: S37-42
Shuldner, A.R., Yang, R., Gong, D.W. (2001) Resistin, obesity, and insulin resistance-the emerging role of the adipocite as an endocrine organ. NEJM, 345, 1345-46
Stojadinovic, M. (2010) Gojaznost i urogenitalno zdravlje. in: Stolić Radojica [ed.] Komorbiditeti gojaznosti i neka odabrana poglavlja, K. Mitrovica, str: 207-219
Stolic, R., Trajkovic, G., Stolic, D., Peric, V., Subaric-Gorgieva, G. (2010) Nutrition parameters as hemodialysis adequacy markers. Hippokratia / Hippokratia, 14(3): 193-7
Stolic, R. (2010) Obesity in renal failure – Health or disease?. Medical Hypotheses, 75(6): 497-500
Stolic, R., Mihailovic, B., Celic, D., Nikolic, G., Stolic, D., Sovtic, S., Trajkovic, G., Sipic, M., Lazic, S. (2010) Characteristics of depression in obese people living in an insecure environment. Indian Journal of Medical Sciences, 64(7): 307
Stolić, R. (2010) Socijalno-medicinski aspekt gojaznosti. in: Stolić R. [ed.] Komorbiditeti gojaznosti i neka odabrana poglavlja, K. Mitrovica, str: 50-60
Thalmann, S., Meier, C.A. (2007) Local adipose tissue depots as cardiovascular risk factors. Cardiovascular Research, 75(4): 690
Uwaifo, G.I., Elif, A. Obesity.
Vaccarino, V., McClure, C., Johnson, D.B., Sheps, D.S., Bittner, V., Rutledge, T., Shaw, L.J., Sopko, G., Olson, M.B., Krantz, D.S., Parashar, S., Marroquin, O.C., Merz, N.B.C. (2008) Depression, the metabolic syndrome and cardiovascular risk. Psychosomatic medicine, 70(1): 40-8
van Kruijsdijk, R.C.M., van der Wall, E., Visseren, F.L.J. (2009) Obesity and Cancer: The Role of Dysfunctional Adipose Tissue. Cancer Epidemiology Biomarkers & Prevention, 18(10): 2569-2578
Young, E.A., Breslau, N. (2004) Cortisol and Catecholamines in Posttraumatic Stress Disorder. Archives of General Psychiatry, 61(4): 394