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2007, vol. 64, br. 3, str. 219-222
Somatostatinom Vaterove papile kod bolesnice s von Reklinghausenovom bolesti
Klinički centar Srbije, Klinika za gastroenterohepatologiju, Beograd
Ključne reči: neurofibromatoza; karcinoid tumor; duodenum; vaterova ampula
Sažetak
Uvod. Somatostatinomi digestivnog trakta luče hormon somatostatin koji može izazvati klinički sindrom poznat kao "inhibitorni sindrom" koji uključuje dijabetes melitus, holelitijazu i steatoreičnu dijareju. Somatostatin luče i D ćelije Langerhansovih ostrvaca, ali i endokrine ćelije u želucu, tankom crevu i pljuvačnim žlezdama kao i tzv. parafolikulne ćelije tiroidne žlezde. Somatostatinomi digestivnog trakta javljaju se u pankreasu i duodenumu. Osobe sa von Reklinghausenovom bolešću su naročito sklone somatostatinomima duodenuma. Prikaz bolesnika. Prikazana je bolesnica stara 51 godinu s von Reklinghausenovom bolešću kod koje je, tokom ispitivanja uzroka opstrukcione žutice, utvrđen tumor Vaterove papile. Učinjena je cefalična duodenopankreatektomija po Whippleu i ekscizija nekoliko neurofibroma sa zida početnog dela jejunuma i sa kože. Histološkim i imunohistohemijskim ispitivanjem tumora utvrđeno je da se radi o tipu B glandulnog karcinoidnog tumora s jakom antisomatostatinskom i pratećom lakom antigastrinskom imunoreaktivnošću. Više od četiri godine posle operacije bolesnica je bez simptoma. Zaključak. Kod bolesnika s von Reklinghausenovom bolešću treba tragati za karcinoidnim tumorom duodenuma i papile, pogotovo u slučaju pojave znakova holestaze.
Reference
Alamowitch, C., Larousse, C. (1982) Association of Recklinghausen's disease with carcinoid of Vater's ampulla. A new nosologic entity: Apudoma. A case. Nouv Presse Med, 11(44): 3255-7
Barber, P.V. (1976) Carcinoid tumour of the ampulla of Vater associated with cutaneous neurofibromatosis. Postgrad Med J, 52(610): 514-7
Bolande, R.P. (1974) The neurocristoapthies: A unifying concept of disease arising in neural crest maldevelopment. Hum Pathol, 5: 409-29
Cantor, A.M., Rigby, C.C., Beck, P.R., Mangion, D. (1982) Neurofibromatosis, phaeochromocytoma, and somatostatinoma. Br Med J (Clin Res Ed), 285(6355): 1618-9
Cohen, C., Heymann, M.F., Michenet, P., Memeteau, F., Saint-Marc, O., Emy, P., Maitre, F., le Bodic, M.F. (2000) Duodenal somatostatinomas associated with von Recklinghausen's neurofibromatosis. Apropos of 2 cases. Ann Pathol, 20(6): 609-11
Dayal, Y., Tallberg, K.A., Nunnemacher, G., DeLellis, R.A., Wolfe, H.J. (1986) Duodenal carcinoids in patients with and without neurofibromatosis. A comparative study. Am J Surg Pathol, 10(5): 348-57
Fendrich, V., Ramaswamy, A., Slater, E.P., Bartsch, D.K. (2004) Duodenal somatostatinoma associated with Von Recklinghausen's disease. J Hepatobiliary Pancreat Surg, 11(6): 417-21
Fujita, T. (1976) The gastro/enteric endocrine cell and its paraneuronic nature. u: Coupland R.E., Fujita T. [ur.] Chromaffin enterochromaffin and related cells, Amsterdam: Elsevier, str. 191-208
Hardt, P.D., Doppl, W.E., Klor, H.U., Hinrichs, B. (1998) A rare combination of pheochromocytoma ans somatostatin-rich neuroendocrine tumor of Vater's papilla (carcinoid) in a patient with von Recklinghausen neurofibromatosis. Z Gastroenterol, 36(3): 233-8
Hochberg, F.H., Dasilva, A.B., Galdabini, J., Richardson, E.P. (1974) Gastrointestinal involvement in von Recklinghausen's neurofibromatosis. Neurology, 24(12): 1144-51
Hope, D.G., Mulvihll, J.J. (1981) Malignancy in neurofibromatosis. u: Riccardi V.M., Mulvihll J.J. [ur.] Neurofibromatosis 'von Recklinghausen disease', New York: Raven Press, str. 33-56
Kheir, S.M., Halpern, N.B. (1984) Paraganglioma of the duodenum in association with congenital neurofibromatosis. Possible relationship. Cancer, 53(11): 2491-6
Mao, C., Shah, A., Hanson, D.J., Howard, J.M. (1995) Von Recklinghausen's disease associated with duodenal somatostatinoma: Contrast of duodenal versus pancreatic somatostatinomas. J Surg Oncol, 59(1): 67-73
Marcial, M.A., Pinkus, G.S., Skarin, A., Hinrichs, H.R., Warhol, M.J. (1983) Ampullary somatostatinoma: Psammomatous variant of gastrointestinal carcinoid tumor: an immunohistochemical and ultrastructural study. Report of a case and review of the literature. Am J Clin Pathol, 80(5): 755-61
Ohtsuki, Y., Sonobe, H., Mizobuchi, T., Takahashi, K., Hayashi, K., Iwata, J., Tahara, E. (1989) Duodenal carcinoid (somatostatinoma) combined with von Recklinghausen's disease. A case report and review of the literature. Acta Pathol Jpn, 39(2): 141-6
Okada, E., Shozawa, T. (1984) Von Recklinghausen's disease (neurofibromatosis) associated with malignant pheochromocytoma. Acta Pathol Jpn, 34(2): 425-34
Reichardt, M., Rexroth, W., Hasslacher, C. (1998) Von Recklinghausen type I neurofibromatosis and neuroendocrine tumor (somatostatinoma) in a 50-year-old woman. Med Klin (Munich), 93(9): 550-3
Rubenstein, A.E., Mytilineoau, C., Yahr, M.D., Revoltella, R.P. (1981) Neurological aspects of neurofibromatosis. u: Riccardi V.M., Mulvihll J.J. [ur.] Neurofibromatosis (Von Recklingahusen's disease), New York: Raven Press, 11-21
Saurenmann, P., Binswanger, R., Maurer, R., Stamm, B., Hegglin, J. (1987) Somatostatin-producing endocrine pancreatic tumor in Recklinghausen's neurofibromatosis. Case report and literature review. Schweiz Med Wochenschr, 117(30): 1134-9
Thannberger, P., Wilhelm, J.M., Derragui, A., Saraceni, O., Kieffer, P. (2001) Von Recklinghausen's disease associated with pancreatic somatostatinoma. Presse Med, 30(35): 1741-3
von Riccardi, V.M. (1981) Recklinghausen neurofibromatosis. N Engl J Med, 305(27): 1617-27
Wheeler, M.H., Curley, I.R., Williams, E.D. (1986) The association of neurofibromatosis, pheochromocytoma, and somatostatin-rich duodenal carcinoid tumor. Surgery, 100(6): 1163-9
 

O članku

jezik rada: srpski
vrsta rada: prikaz slučaja
DOI: 10.2298/VSP0703219C
objavljen u SCIndeksu: 03.12.2007.

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