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2018, vol. 37, iss. 1, pp. 21-23
Fatal intracerebral haemorrhage on dual antiplatelet therapy in patient with myocardial infarction without ST elevation treated with urgent percutaneous coronary intervention: Case report
aMilitary Medical Academy, Clinic for Emergency Internal Medicine, Belgrade
bMilitary Medical Academy, Clinic for Emergency Internal Medicine, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade

emailmarijans74@gmail.com
Keywords: myocardial infarction without ST elevation; dual antiplatelet therapy; percutaneous coronaryintervention; intracranial haemorrhage
Abstract
According to valid guidelines for the use of dual antiplatelet therapy in patients with myocardial infarction without ST elevation (NSTEMI), the use of dual antiplatelet therapy -ASA and ticagrelor is recommended (class I level of evidence B). We report a case of a successful early percutaneous coronary intervention (early PCI) in a patient with a myocardial infarction without ST elevation which received a loding dose ticagrelor after coronary angiography. We found the subtotal stenosis of the right coronary artery and stent implantation is performed.Our case showed implementation of 2015. ESC guidelines on dual antiplatelet therapy in patient with NSTEMI. The procedure was successful without periprocedural complication.but at 22 hours next day patient was intracranial hemorrhage and 48 after patient died.
References
Roffi, M., Patrono, C., Collet, J., Mueller, C., Valgimigli, M., Andreotti, F., Bax, J.J., Borger, M.A., Brotons, C., Chew, D.P., Gencer, B., Hasenfuss, G., Kjeldsen, K., Lancellotti, P. (2015) 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal, 37(3): 267-315
Valgimigli, M., Bueno, H., Byrne, R.A., i dr. (2018) 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS. The Task Force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the Euro. Eur Heart J, 39: 213-254