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Medicinski pregled
2020, vol. 73, br. 1-2, str. 21-28
jezik rada: engleski
vrsta rada: pregledni članak
objavljeno: 20/06/2020
doi: 10.2298/MPNS2002021L
Metode transkranijalnog doplera u proceni cerebralne vazomotorne reaktivnosti
aKlinički centar Vojvodine, Klinika za neurologiju, Novi Sad + Univerzitet u Novom Sadu, Medicinski fakultet
bUniverzitet u Novom Sadu, Medicinski fakultet + Univerzitet u Novom Sadu, Medicinski fakultet, Institut za kardiovaskularne bolesti

e-adresa: aleksandra.lucic-prokin@mf.uns.ac.rs

Sažetak

Uvod. Transkranijalni dopler jedini je neinvazivni neuroimidžing modalitet u dijagnostici i praćenju različitih neurovaskularnih bolesti. Procenjujući cerebralnu hemodinamiku analizom protoka krvi u bazalnim arterijama mozga, transkranijalni dopler dodaje fiziološke podatke anatomskim slikama. Kvantifikaciono ispitivanje vazomotorne reaktivnosti. Pomoću različitih metoda transkranijalnog doplera procene cerebralne vazomotorne reaktivnosti, dobijaju se važne informacije o sposobnosti arteriola u indukovanim hemodinamičkim uslovima. Najčešće se koriste egzogeni i endogeni vazoaktivni stumulusi različite potentnosti (apnea, acetazolamid, ugljen-dioksid, Larginin) čime transkranijalni dopler dobija ulogu prognostičkog pokazatelja budućih ishemijskih događaja. U članku će biti prikazan princip izvođenja različitih metoda transkranijalnog doplera u evaluaciji cerebralne vazomotorne reaktivnosti, uz isticanje prednosti i nedostataka svake od navedenih. Transkranijalni dopler u oblasti redukovane vazomotorne reaktivnosti. Procena cerebralne vazomotorne reaktivnosti ima ulogu prognostičkog pokazatelja budućih ishemijskih događaja; u proceni revaskularizacionog efekta nakon karotidne endarterektomije, ali i sve značajnijeg odabira pravog vremena za njeno izvođenje. Poslednjih godina, metode transkranijalnog doplera našle su primenu i u drugim sferama afunkcionalne cerebralne hemodinamike: demencija, hipertenzija, migrena, sepsa. Zaključak. Sa dobrom vremenskom rezolucijom, neinvazivnim pristupom, dobrim odnosom troškova i koristi, transkranijalni dopler u evaluaciji cerebralne vazomotorne reaktivnosti može biti, skoro pa idealno, sredstvo za procenu intrakranijalne hemodinamike, integriteta arterijske perfuzije i indeksa kolateralnog kapaciteta.

Ključne reči

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