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Vojnosanitetski pregled
2012, vol. 69, br. 7, str. 631-634
jezik rada: engleski
vrsta rada: prikaz slučaja
objavljeno: 24/07/2012
doi: 10.2298/VSP1207631Z
Primarna leptomeningealna melanocitoza
Univerzitet u Nišu, Medicinski fakultet, Katedra Patologija

Projekat

Virtuelni koštano zglobni sistem čoveka i njegova primena u pretkliničkoj i kliničkoj praksi (MPNTR - 41017)

Sažetak

Uvod. Primarna melanocitoza leptomeningi predstavlja redak tumor, koji najverovatnije nastaje od melanocita koji se nalaze u leptomeningama. Prosečno vreme preživljavanja iznosi samo oko pet meseci. Prikaz bolesnika. Prikazana je bolesnica stara 61 godinu koja je imala dvomesečne tegobe - glavobolju, amaurozu i halucinacije, a lečena je u Klinici za psihijatriju i Klinici za infektivne bolesti. Analizom cerebrospinalne tečnosti nađen je snižen nivo glukoze i povišen nivo proteina. Kompjuterizovanom tomografijom i magnetnom rezonancijom viđena su mala zasenčenja bazalnih leptomeningi i hidrocefalus. Obdukcijom na bazalnim leptomeningama uočena je tamnobraon masa sa nejasnim granicama. Pigmentne kožne lezije nisu nađene. Histopatološkom analizom dijagnostikovana je primarna leptomeningealna melanocitoza. Zaključak. Primarna leptomeningealna melanocitoza je redak tumor koji se teško dijagnostikuje. Specifičnost ovog rada je u tome da prikazuje bolesnicu sa oboljenjem koje se retko sreće u praksi.

Ključne reči

Reference

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