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Advanced Technologies
2019, vol. 8, br. 2, str. 16-25
jezik rada: engleski
vrsta rada: izvorni naučni članak
objavljeno: 20/12/2019
doi: 10.5937/savteh1902016C
Nano-biokompleksi na bazi oligosaharida i njihovih derivata
aUniverzitet u Nišu, Tehnološki fakultet, Leskovac
bUniverzitet u Nišu, Medicinski fakultet

e-adresa: cakicm@yahoo.com

Sažetak

Predmet ovog rada je razvoj novih nano-biokompleksa gvožđa, kobalta i bakra na bazi oligosaharida (dekstran, pullulan, inulin) kao i kompleksa bakra i kobalata sa dekstran sulfatom i karboksi metil dekstranom i nanočestica srebra sa derivatima ovih oligosaharida i vodenim ekstraktom Fumaria officinalis L. Ispitivan je uticaj konstitucije liganda na ishod sinteze, prikazani su i rezultati fizičko-hemijskih i spektroskopskih metoda ispitivanja (HPLC, GFC, FTIR, ESR, XRD, EDX, SEM, TEM, UV-Vis, AAS) na osnovu kojih su predloženi modeli strukture ispitivanih nano-biokompleksa. Rezultati ispitivanja stabilnosti i farmako-biološke aktivnosti ukazuju na moguću primenu za izradu različitih farmaceutskih, kozmetičkih i drugih preparata za primenu u humanoj medicini, veterini, kozmetici i drugim oblastima.

Ključne reči

nano-biokompleksi; gvožđe; bakar; kobalt; srebro; oligosharidi; farmako-biološke karakteristike

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