- citati u SCIndeksu: [1]
- citati u CrossRef-u:0
- citati u Google Scholaru:[
 ]
- posete u poslednjih 30 dana:6
- preuzimanja u poslednjih 30 dana:6
|
|
|
2021, vol. 16, br. 1, str. 55-63
|
|
KOVID-19 trijaža hospitalizovanih neonatusa u Tuzlanskom kantonu
COVID-19 triage among hospitalized neonates in Tuzla Canton
aUniversity Clinical Center of Tuzla, Pediatric Clinic, Tuzla, Bosnia and Herzegovina bUniverzitet u Tuzli, Medicinski fakultet, Federacija BiH
e-adresa: devletahadzic@yahoo.com
Sažetak
Cilj studije: da se proceni incidencija, karakteristike, prenos i ishodi infekcije COVID-19 kod hospitalizovanih novorođenčadi u Tuzlanskom kantonu i naglasi važnost kvalitetne trijaže u prevenciji i kontroli infekcije. Metode: Retrospektivna kohortna studija koja je obuhvatila svu uzastopnu novorođenčad suspektnu na infekciju COVID-19 koja su zahtevala nadzor i skrining na odeljenju trijaže, među onim koji su zahtevali hospitalizaciju u Klinici za dečije bolesti Univerzitetskog kliničkog centra Tuzla, tokom 12 meseci. (od 1. januara do 31. decembra 2020. godine). U statističkoj analizi primenjene su standardne metode, a istraživanje je odobrio Etički komitet institucije. Rezultati: U posmatranom periodu, na odeljenju za trijažu lečeno je 111 novorođenčadi pod sumnjom na COVID-19, bez razlike u polnoj zastupljenosti. Među njima je bilo 92 novorođenčadi od majki suspektnih na COVID-19 (66 primljenih odmah nakon rođenja, 26 ponovo primljenih nakon prethodnog otpusta kući) i 19 novorođenčadi od majki pozitivnih na COVID-19 (16 primljenih neposredno nakon rođenja, 3 ponovni prijem). Kod majki pozitivnih na COVID-19, carski rez bio je češća opcija porođaja, a febrilnost češće primećeni simptom, ali bez statističke značajnosti. Novorođenčad od majki suspektnih na COVID-19 su činila heterogenu grupu, sa uobičajenim perinatalnim problemima, dok su novorođenčad od pozitivnih majki, hospitalizovana odmah po rođenju, gotovo svi bili terminska novorođenčad sa odgovarajućom porođajnom težinom, bez potrebe za značajnim lečenjem. Sva novorođenčad hospitalizovana odmah nakon rođenja bila su negativna na COVID-19. Jedino troje novorođenčadi pozitivnih na COVID-19 bilo je hospitalizovano nakon izvesnog boravka kod kuće, svi su imali blage simptome, uglavnom jednodnevnu temperature i svi su se potpuno oporavili. Sva ova novorođenčad nakon hospitalizacije su na daljem praćenju i za sada su dobrog opšteg stanja i svi su na prirodnoj ishrani. Zaključak: Novorođenčad rođena od majki sa potvrđenom infekcijom COVID-19 uglavnom ima povoljne ishode, bez ubedljivog dokaza vertikalnog prenosa. COVID-19 u novorođenčadi je uglavnom stečena postnatalno i povezana sa povoljnim ishodima. Značaj kvalitetne trijaže u prevenciji i kontroli infekcije je presudan, uz doslednu primenu bezbednih praksi, uključujući odgovarajuću izolaciju pacijenta i odgovarajuću zaštitnu opremu.
Abstract
Aim: To evaluate the incidence, characteristics, transmission, and outcomes of COVID-19 infection in hospitalized neonates in Tuzla Canton and to emphasize the importance of quality triage in the prevention and control of infection. Material and Methods: A retrospective cohort study, which included all consecutive neonates suspected of COVID-19 infection, and which required screening supervision in the triage department, from those who required hospital treatment at the Pediatric Clinic, University Clinical Center Tuzla for 12 months. (January 1 to December 31, 2020). Statistical analysis applied standard methods, and the research was approved by the Ethics Committee of the institution. Results: In the observed period, in the neonatal triage department, 111 neonates suspected to COVID-19 were treated, with no gender difference. Among them were 92 neonates of mothers suspected of COVID-19 (66 admitted immediately after birth, 26 readmitted after discharge home), and 19 neonates of mothers positive for COVID-19 (16 admitted immediately after birth, 3 readmitted). Cesarean delivery was a more common delivery option, and fever a more common symptom in COVID-19 positive mothers, but without statistical significance. The neonates from COVID-19 suspected mothers formed a heterogeneous group, with common perinatal problems, while neonates from COVID-19 positive mothers, hospitalized immediately after birth, were almost term neonates with appropriate birth weight, without need for a lot of treatment. All neonates hospitalized immediately after birth were negative for COVID-19. The only three COVID-19 positive neonates were readmitted after previous discharge home, and they had mild symptoms, mostly one-day fever, and they all recovered completely. All of these neonates are under further follow-up after discharge from the hospital, and all are, for now, in good general condition, and all have continued to breastfeed. Conclusion: Neonates born to mothers with positive COVID-19 infection generally have favorable outcomes, with no convincing case of vertical transmission. Neonatal COVID-19 is mostly asymptomatic, acquired postnatally, and associated with favorable outcomes. The importance of quality triage in the prevention and control of infection is crucial, with consistent implementation of safe practices including proper patient isolation and appropriate protective equipment.
|
|
|
|
Reference
|
|
  
|
Chandrasekharan, P., Vento, M., Trevisanuto, D., Partridge, E., Underwood, M.A., Wiedeman, J., et al. (2020) Neonatal Resuscitation and Postresuscitation Care of Infants Born to Mothers with Suspected or Confirmed SARS-CoV-2 Infection. Am J Perinatol, 37(8): 813-824
|
|
|
de Rose, D.U., Piersigilli, F., Ronchetti, M.P., Santisi, A., Bersani, I., Dotta, A., et al. (2020) Novel Coronavirus Disease (COVID-19) in Newborns and Infants: What We Know So Far. Ital J Pediatr, 46(1): 56-56
|
|
|
Gale, C., Quigley, M.A., Placzek, A., Knight, M., Ladhani, S., Draper, E.S., et al. (2021) Characteristics and Outcomes of Neonatal SARS-CoV-2 Infection in the UK: A Prospective National Cohort Study Using Active Surveillance. Lancet Child Adolesc Health, 5(2): 113-121
|
|
|
Golden, T.N., Simmons, R.A. (2020) Maternal and Neonatal Response to COVID-19. Am J Physiol Endocrinol Metab, 319(2): E315-E319
|
|
|
Griffin, I., Benarba, F., Peters, C., Oyelese, Y., Murphy, T., Contreras, D., et al. (2020) The Impact of COVID-19 Infection on Labor and Delivery, Newborn Nursery, and Neonatal Intensive Care Unit: Prospective Observational Data from a Single Hospital System. Am J Perinatol, 37(10): 1022-1030
|
|
|
Halliday, H.L., Speer, C.P. (2020) COVID-19 and Neonatal Resuscitation. Neonatology, 117(2): 132-132
|
|
|
Jain, P., Thakur, A., Kler, N., Garg, P. (2020) Manifestations in Neonates Born to COVID-19 Positive Mothers. Indian J Pediatr, 87(8): 644-644
|
|
|
Juan, J., Gil, M.M., Rong, Z., Zhang, Y., Yang, H., Poon, L.C. (2020) Effect of Coronavirus Disease 2019 (COVID-19) on Maternal, Perinatal and Neonatal Outcome: Systematic Review. Ultrasound Obstet Gynecol, 56(1): 15-27
|
|
|
Karimi-Zarchi, M., Neamatzadeh, H., Dastgheib, S.A., Abbasi, H., Mirjalili, S.R., Behforouz, A., et al. (2020) Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review. Fetal Pediatr Pathol, 39(3): 246-250
|
|
|
Sankar, J., Dhochak, N., Kabra, S.K., Lodha, R. (2020) COVID-19 in Children: Clinical Approach and Management. Indian J Pediatr, 87(6): 433-442
|
|
|
Shalish, W., Lakshminrusimha, S., Manzoni, P., Keszler, M., Sant'anna, G.M. (2020) COVID-19 and Neonatal Respiratory Care: Current Evidence and Practical Approach. Am J Perinatol, 37(8): 780-791
|
|
|
Smith, V., Seo, D., Warty, R., Payne, O., Salih, M., Chin, K.L., et al. (2020) Maternal and Neonatal Outcomes Associated with COVID-19 Infection: A Systematic Review. PLoS One, 15(6): e0234187
|
|
|
Sporisevic, L., Mesihović-Dinarevic, S., Joguncic, A., Pilav, A. (2020) Coronavirus Disease 2019 (COVID-19): A New Pediatric Challenge. JHSCI, 10(2): 103-108
|
|
|
Tezer, H., Demirdağ, B.T. (2020) Novel Coronavirus Disease (COVID-19) in Children. Turk J Med Sci, 50(SI-1): 592-603
|
|
|
Yeo, K.T., Oei, J.L., de Luca, D., Schmolzer, G.M., Guaran, R., Palasanthiran, P., et al. (2020) Review of Guidelines and Recommendations from 17 Countries Highlights the Challenges That Clinicians Face Caring for Neonates Born to Mothers with COVID-19. Acta Paediatr, 109(11): 2192-2207
|
|
|
Zaigham, M., Andersson, O. (2020) Maternal and Perinatal Outcomes with COVID-19: A Systematic Review of 108 Pregnancies. Acta Obstet Gynecol Scand, 99(7): 823-829
|
|
1
|
Zimmermann, P., Curtis, N. (2020) Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children. Pediatr Infect Dis J, 39(5): 355-368
|
|
|
|
|