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2016, vol. 69, br. 3-4, str. 93-98
Infekcija virusom krpeljskog meningoencefalitisa kod ljudi
aUniverzitet u Novom Sadu, Medicinski fakultet + Institute for Public Health of Vojvodina, Novi Sad Centre for Virology
bInstitute for Public Health of Vojvodina, Novi Sad Centre for Virology
cUniverzitet u Novom Sadu, Medicinski fakultet

e-adresaivana.hrnjakovic-cvjetkovic@mf.uns.ac.rs
Ključne reči: Krpeljni encefalitis; Bolesti izazvane krpeljima; Virus krpeljnog encefalitisa; Dijagnoza; Epidemiologija; Prenos zaraznih bolesti; Neurološke manifestacije; Vakcinacija; Endemske bolesti; Zoonoze
Sažetak
Uvod. Virus krpeljskog meningoencefalitisa je flavivirus, uzročnik najznačajnije vektorske infekcije centralnog nervnog sistema u mnogim zemljama Evrope i Azije. Postoje tri podtipa virusa krpeljskog meningoencefalitisa: evropski, sibirski i dalekoistočni. Prenošenje. U endemskim područjima virus se održava u transmisivnom ciklusu između krpelja roda Ixodes i malih glodara. Klinička slika. U većini slučajeva (70-98%) infekcija je asimptomatska. Kod oko jedne trećine slučajeva meningitisa razvijaju se meningoencefalitis ili meningomijelitis. Kao komplikacija infekcije može se razviti postencefalitisni sindrom, ispoljen neurološkim manifestacijama. Dijagnoza. Etiološka dijagnoza krpeljskog meningoencefalitisa zasniva se na laboratorijskim analizama. Reakcija lančane polimerizacije sa reverznom transkripcijom primenjuje se za dokazivanje virusne nukleinske kiseline u serumu i likvoru. Antitela protiv virusa krpeljskog meningoencefalitisa mogu biti dokazana serološkim testovima. Prevencija. Najefikasniji način kontrole ove potencijalno opasne bolesti sa mogućim dugotrajnim posledicama je vakcinacija. Vakcina se preporučuje osobama koje žive ili putuju u endemske krajeve. Zaključak. U Srbiji je ova infekcija na listi bolesti koje podležu obaveznom prijavljivanju, no prijavljenih slučajeva nema jer se dijagnostika ne sprovodi rutinski. Smatramo da bi trebalo ispitati značaj koji ova zoonoza ima u našoj zemlji i pojedinim njenim područjima zbog nalaza seropozitivnih u prvim preliminarnim serološkim ispitivanjima sprovedenim u Vojvodini, zbog slučajeva koji se registruju u susednoj Mađarskoj i Hrvatskoj kao i rasprostranjenosti ove infekcije u svetu.
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O članku

jezik rada: engleski
vrsta rada: pregledni članak
DOI: 10.2298/mpns1604093H
objavljen u SCIndeksu: 27.04.2016.

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