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Serbian Journal of Anesthesia and Intensive Therapy
2011, vol. 33, iss. 3-4, pp. 249-253
article language: Serbian
document type: Discussion/Paper
Ventilator associated pneumonia: Etiopathogenesis, prevention and diagnosis
aMedicinski fakultet, Beograd + Centar za anesteziju Kliničkog centra Srbije, Beograd
bCentar za anesteziju Kliničkog centra Srbije, Beograd



Ventilator associated pneumonia (VAP) is one of the most common intrahospital infections and may be caused by a wide spectrum of bacterial pathogens. Depends on time of onset may be caused by antibiotic-sensitive or antibiotic-resistant pathogens. Aspiration of oropharyngeal pathogens or leakage of bacteria around the endotracheal tube cuff is the primary route of bacterial entry into the trachea intubated patients. The importance of VAP in terms of morbidity, mortality, lenght of hospital stay and costs, makes prevention (non-pharmacologic and pharmacologic) an important issue. If ventilator associated pneumonia occurs, early diagnosis is necessary due to accurate choice of antimicrobial therapy. Sometimes ventilator-associated pneumonia (VAP) is difficult to diagnose and diagnosis is based on clinical feature, radiographic examination and microbiologic results.



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