Metrika

  • citati u SCIndeksu: 0
  • citati u CrossRef-u:0
  • citati u Google Scholaru:[]
  • posete u poslednjih 30 dana:5
  • preuzimanja u poslednjih 30 dana:4

Sadržaj

članak: 1 od 1  
2013, vol. 47, br. 1, str. 36-38
Sindrom nemirnih nogu
'Zastava' Zavod za zdravstvenu zaštitu radnika, Kragujevac

e-adresaanamladicevic@yahoo.com
Sažetak
Sindrom nemirnih nogu (engl. Restless Legs Syndrome - RLS) ili Ekbomov sindrom je poremećaj koji se karakteriše neodoljivim nagonom za pokretanjem nogu, kako bi se zaustavile neprijatne senzacije. On se ubraja u neurološke poremećaje pokreta i ima prevalencu između 7-10%. Patofiziologija RLS nije sasvim jasna, a istraživanja ukazuju na to da je uzrok funkcionalni poremećaj dopaminske funkcije i da RLS može biti primaran ili sekundaran. Farmakoterapija primarnog RLS uključuje agoniste dopamina kao prvi lek za bolesnike sa svakodnevnim simptomima, opijate i antikonvulzive za rezistentne slučajeve, levodopu i benzodiazepine. U sekundarnom RLS koriste se preparati gvožđa. Lekari različitih specijalnosti susreću se s bolesnicima koji imaju RLS, ali ga zbog nedovoljne edukovanosti retko dijagnostikuju.
Reference
*** (2010) Restless legs syndrome fact sheet. u: NIH Publication No. 10-4847, Bethesda: National Institutes of Health, http://www.ninds.nih.gov/disorders/restless_legs/detail_restless_legs.htm
Allen, R.P., Connor, J.R., Hyland, K., Earley, C.J. (2009) Abnormally increased CSF 3-Ortho-methyldopa (3-OMD) in untreated restless legs syndrome (RLS) patients indicates more severe disease and possibly abnormally increased dopamine synthesis. Sleep medicine, 10(1): 123-8
Berger, K., Luedemann, J., Trenkwalder, C., John, U., Kessler, C. (2004) Sex and the risk of restless legs syndrome in the general population. Arch Intern Med, 164(2): 196-202
Coccagna, G., Vetrugno, R., Lombardi, C., Provini, F. (2004) Restless legs syndrome: an historical note. Sleep medicine, 5(3): 279-83
Earley, C.J., Silber, M.H. (2010) Restless legs syndrome: understanding its consequences and the need for better treatment. Sleep medicine, 11(9): 807-15
Earley, C.J. (2003) Restless Legs Syndrome. New England Journal of Medicine, 348(21): 2103-2109
Gamaldo, C.E., Earley, C.J. (2006) Restless legs syndrome: A clinical update. Chest, 130(5): 1596
Garcia-Borreguero, D., Stillman, P., Benes, H., Buschmann, H., Chaudhuri, R.K., Gonzalez, R.V.M., Högl, B., Kohnen, R., Monti, G.C., Stiasny-Kolster, K., Trenkwalder, C., Williams, A., Zucconi, M. (2011) Algorithms for the diagnosis and treatment of restless legs syndrome in primary care. BMC neurology, 11: 28
Karatas, M. (2007) Restless legs syndrome and periodic limb movements during sleep: diagnosis and treatment. neurologist, 13(5): 294-301
Kurlan, R. (2004) Postprandial (reactive) hypoglycemia and restless leg syndrome: related neurologic disorders?. Mov Dis, 13: 619-620
Lavigne, G.J., Montplaisir, J.Y. (1994) Restless legs syndrome and sleep bruxism: Prevalence and association among Canadians. Sleep, 17(8): 739-43
McDonagh, B., King, T., Guptan, R.C. (2007) Restless legs syndrome in patients with chronic venous disorders: an untold story. Phlebology, 22(4): 156-63
Pantaleo, N.P., Hening, W.A., Allen, R.P., Earley, C.J. (2010) Pregnancy accounts for most of the gender difference in prevalence of familial RLS. Sleep medicine, 11(3): 310-3
Rottach, K.G., Schaner, B.M., Kirch, M.H., Zivotofsky, A.Z., Teufel, L.M., Gallwitz, T., Messer, T. (2008) Restless legs syndrome as side effect of second generation antidepressants. Journal of psychiatric research, 43(1): 70-5
Sladojević, N., Knežević, M., Jović, J., Đorđević, V. (2012) Sindrom nemirnih nogu kod pacijenata na hemodijalizi - učestalost, težina i faktori rizika. Medicinski časopis, vol. 46, br. 3, str. 138-144
Stefansson, H., Rye, D.B., Hicks, A., Petursson, H., Ingason, A., Thorgeirsson, T.E., Palsson, S., Sigmundsson, T., Sigurdsson, A.P., Eiriksdottir, I., Soebech, E., Bliwise, D., Beck, J.M. (2007) A genetic risk factor for periodic limb movements in sleep. New England journal of medicine, 357(7): 639-47
Xiong, L., Montplaisir, J., Desautels, A., Barhdadi, A., Turecki, G., Levchenko, A., Thibodeau, P., Dubé, M., Gaspar, C., Rouleau, G.A. (2010) Family study of restless legs syndrome in Quebec, Canada: clinical characterization of 671 familial cases. Archives of neurology, 67(5): 617-22
 

O članku

jezik rada: srpski
vrsta rada: prikaz
DOI: 10.5937/mckg47-2820
objavljen u SCIndeksu: 05.03.2013.

Povezani članci