Metrika članka

  • citati u SCindeksu: 0
  • citati u CrossRef-u:0
  • citati u Google Scholaru:[=>]
  • posete u prethodnih 30 dana:10
  • preuzimanja u prethodnih 30 dana:5
članak: 1 od 1  
Medicinski časopis
2018, vol. 52, br. 1, str. 7-14
jezik rada: engleski
vrsta rada: izvorni naučni članak
doi:10.5937/mckg52-16885


Analiza 3D slike minornih pljuvačnih žlezda kod pacova rođenih sa makrozomijom i starih 180 dana
aKharkiv National Medical University, Therapeutic Dentistry Department, Kharkiv, Ukraine
bKharkiv National Medical University, Pathological Anatomy Department, Kharkiv, Ukraine
cInstitute of Physiology of the Czech Academy of Sciences, Department of Biomathematics, Prague, Czech Republic

e-adresa: o.v.garmash@gmail.com

Projekat

This work was supported by the BioImaging Facility, Institute of Physiology, supported by the Czech-BioImaging large RI project (LM2015062 funded by MEYS CR) and by the project Modernization and support of research activities of the national infrastructure for biological and medical imaging Czech-BioImaging (CZ.02.1.01/0.0/0.0/16_013/0001775 funded by OP RDE)

Sažetak

Cilj. Odrediti morfometrijske razlike minornih bukalnih pljuvačnih žlezda kod pacova starih 6 meseci sa fetalnom makrozomijom (ispitivana grupa) i kod pacova starih 6 meseci nakon normalnog intrauterinog razvoja (kontrolna grupa), korišćenjem tehnike 3-D analize. Metodologija. Fetalna makrozomija je indukovana na 4 različita načina. Kako bi se sprovela morfološka analiza, korišćena su tkiva sluznice usne duplje kod šestomesečnih pacova. Procena morfometrijskih karakteristika mikroskopskih struktura minornih bukalnih pljuvačnih žlezda je vršena korišćenjem 3-D slika dobijenih konfokalnom mikroskopijom. Rezultati. Nakon dostizanja starosti od 6 meseci, potomci pacova svih makrozomijskih grupa su imali prosečnu telesnu težinu, dužinu i odnos težina-dužina u poređenju sa kontrolnom grupom. Kod pacova rođenih sa različitim modelima fetalne makrozomije, nakon postizanja starosti od 6 meseci, devijacije u ispitivanim grupama u odnosu na kontrolnu grupu su pronađene u različitim stepenima sledećih parametara: površina acinusa, površina acinusne šupljine, broj mukoznih acinusnih ćelija u acinusu, visina citoplazme u mukoznim acinusnim ćelijama, procenat frakcije relativne površine poprečnog preseka mukoznih acinusnih ćelija, površina poprečnog preseka acinusne šupljine i relativna površina žlezdane strome. Zaključak. Procena klaster tehnike ovih devijacija dovela nas je do zaključka o postajanju hipoplazije kod minornih bukalnih pljuvačnih žlezda kod pacova rođenih sa fetalnom makrozomijom.

Ključne reči

Reference

Cunha-Cruz, J., Scott, J., Rothen, M., Mancl, L., Lawhorn, T., Brossel, K., Berg, J. (2013) Salivary characteristics and dental caries. Journal of the American Dental Association, 144(5): e31-e40
Eržen, I., Janáček, J., Kubínová, L. (2011) Characterization of the capillary network in skeletal muscles from 3D data. Physiol Res, 60: 1-13
Fracaro, M., Linnett, V., Hallett, K., Savage, N. (2002) Submandibular gland aplasia and progressive dental caries: A case report. Australian Dental Journal, 47(4): 347-350
Godfrey, K.M., Barker, D.J. (2000) Fetal nutrition and adult disease. American journal of clinical nutrition, 71(5 Suppl): 1344S-52S
Gu, S., An, X., Liang, F., Zhang, X., Zhang, C., Wang, J., Liu, Q., Zhang, Y., Wei, Y., Hu, Z., Chen, F., Shen, H. (2012) Risk factors and long-term health consequences of macrosomia: a prospective study in Jiangsu Province, China. Journal of Biomedical Research, 26(4): 235-240
Gubina-Vakulyk, G. (1994) Patologichna anatomiia endokrynnyh zaloz plodu pry adaptatsii vagitnoi do dii okremyh seredovyshchnyh faktoriv [Pathological anatomy of the fetal endocrine glands in pregnant woman adaptation to the some environmental factors action]. Kharkiv National Medical University, Doktor medychnyh nauk: 14. 00. 15, In Ukrainian
Hermann, G.M., Dallas, L.M., Haskell, S.E., Roghair, R.D. (2010) Neonatal Macrosomia Is an Independent Risk Factor for Adult Metabolic Syndrome. Neonatology, 98(3): 238-244
Hodgson, T.A., Shah, R., Porter, S.R. (2001) The investigation of major salivary gland agenesis: a case report. Pediatr Dent, 23: 131-4
Huraseva, A.B. (2007) Substantiation of the differentiated approach to a dispensary observation of the girls who have been born with different birth weight. J of Obst and Womenʼs Diseases, 3: 37-43; in Russian
Janáček, J., Čapek, M., Michálek, J., Karen, P., Kubínová, L. (2014) 3D microscopic imaging and evaluation of tubular tissue architecture. Physiol Res, 63: S49-55
Julihn, A., Molund, U., Drevsäter, E., Modéer, T. (2014) High Birth Weight Is a Risk Factor of Dental Caries Increment during Adolescence in Sweden. Dentistry Journal, 2(4): 118-133
Koyanagi, A., Zhang, J., Dagvadorj, A., Hirayama, F., Shibuya, K., Souza, J.P., Gülmezoglu, A.M. (2013) Macrosomia in 23 developing countries: an analysis of a multicountry, facility-based, cross-sectional survey. Lancet, 381(9865): 476-483
Kubínová, L., Janáček, J. (2015) Confocal stereology: an efficient tool for measurement of microscopic structures. Cell and Tissue Research, 360(1): 13-28
Kubínová, L., Mao, X.W., Janáček, J. (2013) Blood Capillary Length Estimation from Three-Dimensional Microscopic Data by Image Analysis and Stereology. Microscopy and Microanalysis, 19(04): 898-906
Lahmann, P.H., Wills, R., Coory, M. (2009) Trends in birth size and macrosomia in Queensland, Australia, from 1988 to 2005. Paediatric and Perinatal Epidemiology, 23(6): 533-541
Redman, R. (2012) Morphologic diversity of the minor salivary glands of the rat: fertile ground for studies in gene function and proteomics. Biotechnic & Histochemistry, 87(4): 273-287
Redman, R. (2008) On approaches to the functional restoration of salivary glands damaged by radiation therapy for head and neck cancer, with a review of related aspects of salivary gland morphology and development. Biotechnic & Histochemistry, 83(3-4): 103-130
Samaras, T.T., Elrick, H., Storms, L.H. (2003) Birthweight, rapid growth, cancer, and longevity: a review. J Natl Med Assoc, 95: 1170-83
Schindelin, J., Arganda-Carreras, I., Frise, E., Kaynig, V., Longair, M., Pietzsch, T., Preibisch, S., Rueden, C., Saalfeld, S., Schmid, B., Tinevez, J., White, D.J., Hartenstein, V., Eliceir (2012) Fiji: an open-source platform for biological-image analysis. Nature Methods, 9(7): 676-682
Shetty, C., Hegde, M.N., Devadiga, D. (2013) Correlation between dental caries with salivary flow, ph, and buffering capacity in adult south Indian population: an in-vivo study. International Journal of Research in Ayurveda and Pharmacy, 4(2): 219-223
Tandon, A., Singh, N., Sreedhar, G. (2013) Minor salivary glands and dental caries: Approach towards a new horizon. Journal of Natural Science, Biology and Medicine, 4(2): 364
Wolff, M.S., Mirels, L., Lagner, J., Hand, A.R. (2001) Development of the rat sublingual gland: A light and electron microscopic immunocytochemical study. Anatomical Record, 266(1): 30-42
Xuedong, Z. (2016) Dental caries: Principles and management. Berlin Heidelberg: Springer-Verlag, 1th ed
Yokomichi, H., Tanaka, T., Suzuki, K., Akiyama, T., Yamagata, Z. (2015) Macrosomic Neonates Carry Increased Risk of Dental Caries in Early Childhood: Findings from a Cohort Study, the Okinawa Child Health Study, Japan. PLoS One, 10(7): e0133872
Zhang, X., Decker, A., Platt, R.W., Kramer, M.S. (2008) How big is too big? The perinatal consequences of fetal macrosomia. American Journal of Obstetrics and Gynecology, 198(5): 517.e1-517.e6