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Praxis medica
2019, vol. 48, br. 2, str. 15-23
jezik rada: srpski
vrsta rada: originalan članak
objavljeno: 20/09/2019
doi: 10.5937/pramed1902015M
Creative Commons License 4.0
Kliničke i morfološke karakteristike malignog melanoma
Univerzitet u Prištini sa privremenim sedištem u Kosovskoj Mitrovici, Medicinski fakultet

e-adresa: jasminamitrovic88@hotmail.com

Sažetak

Melanom je najagresivniji tumor kože koji ima sklonost ranom limfogenom i hematogenom metastaziranju. Hirurška ekscizija predstavnja metod lečenja. Rana dijagnoza je ključ uspešnog lečenja melanoma koja je primarno povezana sa Breslow i Clark stepenovanjem. Cilj našeg rada bio je ispitati pored ovih i druge prognostičke parametre kao što je starosna, polna i anatomska distribucija melanoma, makroskopski i histološki tip melanoma, veličina i prisustvo ostataka tumorskog tkiva na linijama resekcije. U istraživanju je korišćen biopsijski materijal Instituta za patologiju Medicinskog fakulteta u Prištini od 2004-2017. godine. Analiza podataka pokazala je da je melanom češći kod starijih muškaraca (prosečne starost od 68.5±14.6 godina) najčešće lokalizacije na leđima, zatim na glavi i vratu, gornjim i donjim ekstremitetima, kod kojih je češća pojava metastaza (Clark IV). Veći tumori zahtevaju širu eksciziju. Najveću učesalost pokazuje nodularni tip melanoma a dominantan histološki tip bio je epiteloidni. Između veličine tumorske promene i dubine invazije postoji statistički značajna osrednja pozitivna korelacija, što navodi na zaključak da se Clark i Breslow mogu koristiti kao prognostički faktori jer su međusobno komparativni.

Ključne reči

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