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Acta medica Medianae
2020, vol. 59, br. 1, str. 36-43
jezik rada: engleski
vrsta rada: izvorni naučni članak
objavljeno: 13/09/2020
doi: 10.5633/amm.2020.0105
Creative Commons License 4.0
Rani postoperativni ishodi hirurški tretirane aortne disekcije kod bolesnika sa Marfanovim sindromom
aUniverzitet u Beogradu, Medicinski fakultet, Institut za kardiovaskularne bolesti 'Dedinje'
bUniverzitet u Beogradu, Medicinski fakultet + Klinički centar Srbije, Klinika za ginekologiju i akušerstvo, Beograd
cUniverzitet u Beogradu, Medicinski fakultet, KBC 'Dr Dragiša Mišović'
dUniverzitet u Beogradu, Medicinski fakultet, Institut za kardiovaskularne bolesti 'Dedinje' + Univerzitet u Beogradu, Medicinski fakultet

e-adresa: dr.inesic@gmail.com

Sažetak

Akutna disekcija aorte ostaje vodeći uzrok morbiditeta i mortaliteta bolesnika sa Marfanovim sindromom. Studija je imala za cilj da ispita rane postoperativne ishode hirurški tretirane disekcije aorte kod bolesnika sa Marfanovim sindromom. Studija je obuhvatila sve bolesnike operisane zbog disekcije aorte na Klinici za kardiohirurgiju Instituta za kardiovaskularne bolesti "Dedinje" u Beogradu, tokom perioda od šest godina (2012. - 2017.). Bolesnici su bili podeljeni u odnosu na postojanje dijagnoze Marfanovog sindroma. Preoperativno od svakog bolesnika uzeti su opšti podaci i detaljna medicinska istorija. Nakon prijema, bolesnici su bili podvrgnuti temeljnom kliničkom i kardiološkom pregledu. Bolesnici su hirurški tretirani prema aktuelnim protokolima. Postoperativno, bolesnici su praćeni mesec dana. Tokom ovog perioda praćenja registrovane su sve komplikacije i registrovana je smrtnost. Svi preoperativno i postoperativno prikupljeni podaci upoređeni su i statistički analizirani. Studija je obuhvatila 246 bolesnika od kojih je 7,7% imalo Marfanov sindrom. Bolesnici sa Marfanovim sindromom bili su značajno mlađi od bolesnika kontrolne grupe (p = 0,001). Nije bilo značajnih razlika između grupa bolesnika u pogledu pola i pušačkog statusa. Svi bolesnici sa Marfanovim sindromom imali su disekciju tipa I. Bolesnici sa Marfanovim sindromom imali su manje preoperativnih hroničnih bolesti i komplikacija (p = 0,001). Nije bilo značajnih razlika u mortalitetu (p = 0,702) i učestalosti postoperativnih komplikacija (p = 0,231) između bole-snika sa Marfanovim sindromom i bez Marfanovog sindroma. U zaključku se može videti da brza i adekvatna dijagnoza i hirurško lečenje disekcije aorte mogu omogućiti uglavnom dobre rane postoperativne ishode kod bolesnika sa Marfanovim sindromom.

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