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2018, vol. 37, iss. 2, pp. 64-68
Clinical responce to cardiac resynchronisation therapy
aGeneral hospital Vrbas
bGeneral hospital Požarevac
Keywords: heart failure; cardiac resyinchronization therapy
Introduction: Cardiac resynhronisation therapy (CRT) improves symptoms of systolic heart failure (HF), functional ability and quality of life, reduces mortality and increases life expectancy. Objective: The aim of this study was to present results in the treatment of systolic HF using CRT, at least 12 months after the implantation. Methods: The analysis was retrospective and presents the effects of CRT therapy in 105 patients, mean age 63 ± 8.7 , with QRS width 159.1 ± 23.1 msec in NYHA HF II, III and ambulatory class IV, with optimal medical therapy. Among the patients, 36 of them had HF as a result of ischemic cardiomyopathy (ICM) - previous myocardial infarction had 25 patients (23.8%), and 69 of them had hearth failure of non-ischemic origin. Results: A year after CRT stimulation, there was a statistically significant reduction of the QRS width, reduction in NYHA HF class, extension of the distance by 6MHWT, improvement of LVEF, and number of hospitalizations after procedure. In this study, 60% of patients were responders to CRT, 15% belong to the group of super responders, and 25% in this analysis were non- responders to CRT. Conclusion: In our population, CRT treatment reduced mortality, clinical condition improved, as well as the quality of life in patients with symptomatic systolic HF.
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Yamashita, S., Fukuzawa, K., Yoshida, A., Itoh, M., Imamura, K., Fujiwara, R., Suzuki, A., Nakanishi, T., Matsumoto, A., Kanda, G., Kiuchi, K., Shimane, A., Okajima, K., Tanaka, H., Hirata, K. (2015) The effectiveness of cardiac resynchronization therapy for patients with New York Heart Association class IV non-ambulatory heart failure. Journal of Arrhythmia, 31(4): 221-225


article language: English
document type: Original Paper
DOI: 10.5937/siks1802064D
published in SCIndeks: 12/05/2019

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