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2020, vol. 37, br. 1, str. 48-56
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Ispitivanje efikasnosti antiejdžing liposomskog gela - in vivo dugotrajna studija
Investigation of efficacy of anti-aging liposomal intimate gel: An in vivo long-term study
Sažetak
Liposomi se već decenijama koriste kao univerzalni nosači, a koriste se i za inkapsulaciju mnogih jedinjenja sa različitim kozmetičkim efektima kako bi se postigli kvalitet, bezbednost i efikasnost funkcionalnih kozmetičkih proizvoda. U ovoj studiji, ispitivana je efikasnost primene komercijalnog liposomskog gela (SOPHY Anti-Age Liposomal Intimate Gel), koji sadrži L-arginin, ekstrakt bele kurkume, hijaluronsku kiselinu, mlečnu kiselinu i vitamin E (za koje je ranije pokazano da imaju različite pozitivne efekte na koži), kao inkapsulirane kozmetički aktivne sastojke, in vivo na zdravim dobrovoljcima. Tokom dugoročne dvadesetosmodnevne studije praćeni su biofizički parametri kože (vlažnost kože, TEGV, EI i pH). Kao rezultat, došlo je do povećanja hidratacije kože , smanjenja TEGV i blagog pada EI i pH kože. Dakle, ispitivani kozmetički proizvod ima pozitivan efekat na hidrataciju kože, doprinosi obnavljanju barijerne funkcije kože, a pokazuje i antiiritantne efekte.
Abstract
Liposomes have been used as universal carriers for decades, encapsulating many compounds with different cosmetic effects in order to achieve the quality, safety and efficacy of functional cosmetic products. In the present study, the efficacy of the application of the commercial liposome gel (SOPHY Anti-Aging Liposomal Intimate Gel), containing L-arginine, white curcuma extract, hyaluronic acid, lactic acid and vitamin E (previously shown to have various positive effects on the skin) as encapsulated cosmetic active ingredients, was examined in vivo on healthy volunteers. During a long-term 28-day study, biophysical skin parameters (skin humidity, TEWL, EI and pH) were monitored. As a result, an increase in skin hydration, decrease in TEWL, and a slight decrease in EI and skin pH were observed. Thus, the examined cosmetic product has shown a positive effect on skin hydration, contributing to the renewal of skin barrier, also having the anti-irritating effects.
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