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2021, vol. 149, br. 3-4, str. 179-184
Klinička i radiološka evaluacija spojenih patoloških preloma posle zatvorenog intramedularnog zakivanja i pomoćne radioterapije - retrospektivna studija
aIstanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Department of Orthopedics, Istanbul, Turkey
bAnkara Occupational and Environmental Diseases Hospital, Department of Orthopedics, Ankara, Turkey
cUniversity of Cincinnati Medical Center, Department of Orthopedic Surgery, Cincinnati, OH, United States
dAzienda Ospedaliera Istituto Ortopedico Gaetano Pini, Department of Orthopedic Oncology, Milan, Italy

e-adresaerhanokay@yahoo.com
Ključne reči: patološki prelom; intramedularno zakivanje; pomoćna radioterapija; zarastanje kostiju
Sažetak
Uvod/Cilj Patološki prelomi su teške komplikacije kod metastatske bolesti kostiju. Lečenje ovih stanja varira i uključuje sistemske terapije i hirurške intervencije. Manjak dokaza i dalje postoji za standardizovanu negu. Cilj ove studije je da se analizira odgovor na radiološko lečenje i kliničke ishode posle intramedularnog zakivanja, i pomoćne radioterapije u kompletnim patološkim prelomima butne ili nadlaktične kosti. Metode Retrospektivno je pregledano 19 bolesnika koji su imali patološki prelom. Podaci o demografskim karakteristikama, kliničkim ishodima i radiološkim slikama dobijeni su iz bolničkih kartona. Svi bolesnici u ovoj studiji lečeni su zatvorenim, nerimovanim intramedularnim zakivanjem (NIZ) i pomoćnim tretmanom zračenja. Rezultati Ublažavanje bola i puni opseg pokreta postignuti su kod svih bolesnika. Srednji postoperativni rezultati Društva za mišićno-skeletne tumore na poslednjem praćenju bili su 69% (raspon 50-85%). Svi bolesnici su pokazali potpuno radiografsko zarastanje posle dva-šest meseci. Samo jednom bolesniku je bila potrebna reoperacija radi preloma na vrhu klina, koji je zamenjen dužim klinom. Zaključak Naša studija je pokazala da su patološki prelomi upravljani zatvorenim neinficiranim NIZ i adjuvantnom multifrakcionom radioterapijom od 20 Gy dali dobre kliničke rezultate sa potpunim radiološkim odgovorom bez obzira na očekivani životni vek bolesnika, adjuvantne tretmane i ukupno stanje. Zatvoreni nerimovani NIZ takođe je povezan sa smanjenim vremenom operacije kod ovih visokorizičnih bolesnika.
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O članku

jezik rada: engleski
vrsta rada: originalan članak
DOI: 10.2298/SARH210114019O
primljen: 14.01.2021.
revidiran: 03.03.2021.
prihvaćen: 17.03.2021.
objavljen onlajn: 22.03.2021.
objavljen u SCIndeksu: 18.05.2021.

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