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2017, vol. 56, iss. 3, pp. 137-142
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Demographic characteristics of basal cell carcinoma: A retrospective study of 1884 lesions
Demografske karakteristike bazocelularnog karcinoma - retrospektivna studija 1884 promene
aUniveristy of Niš, Faculty of Medicine + Clinical Centre Niš, Clinic of Plastic and Reconstructive Surgery bClinical Centre Niš, Clinic of Plastic and Reconstructive Surgery cPharmaceutical company 'Pharma Swiss', Niš dDental practice 'Your dentist', Aleksinac
email: gste66@yahoo.com
Abstract
Basal cell carcinoma represents one of the most frequent skin cancers, accounting for around 75% of all skin cancers. Numerous etiological factors contribute to its development (from the genetics to sun exposure). To present the demographic characteristics and distribution of basal cell carcinoma and to evaluate the topography of lesions and their correlations with gender, age, location, size and recurrence rate. This retrospective study included 1734 patients with 1884 lesions, treated at the Clinic of Plastic and Reconstructive Surgery at the Clinical Center Niš, from January 2012 to December 2016. The following parameters were evaluated: age, gender, location, size, histologic type, margin of excision and recurrence rate. Out of the total of 1884 tumors, there were 1621 primary and 263 recurrent cases. High risk localizations included 82.8% of primary and 68.4% of recurrent tumors. With respect to gender, primary tumors were present in 56% of men and 44% of women, while recurrent tumors were present in 41.8% of men and 58.2% of women. Concerning the tumor size, 85.3% of primary and 72.6% of recurrent tumors had a maximum of 2 cm in diameter, whereas 14.7% of primary and 27.4% of recurrent tumors had a diameter of over 2 cm. Complete excision represents a key surgical treatment of basal cell skin cancer. The obtained algorithm can be a useful guide for the monitoring and surgical treatment of basal cell skin cancer.
Sažetak
Bazocelularni karcinom je najčešći tumor kože i čini oko 75% svih tumora kože. Brojni su etiološki faktori odgovorni za njegov nastanak, od genetskih do faktora sredine, kao što je na primer izlaganje suncu. Cilj rada bio je da prikaže demografske karakteristike i distribuciju bazocelularnog karcinoma i da proceni povezanost lokalizacije lezija sa polom, veličinom, stepenom recidiva. Retrospektivna studija obuhvatila je 1734 bolesnika sa 1884 promene, koji su lečeni na Klinici za plastičnu i rekonstruktivnu hirurgiju Kliničkog centra u Nišu od januara 2012. do decembra 2016. godine. Ispitivani su sledeći parametri: starost, pol, lokalizacija, histološki tip, margine ekscizije i stepen recidiva. Od ukupno 1884 promene, 1621 je bila primarna, a 263 su bile recidivi bazo-celularnog karcinoma. Sa visokorizičnim lokalizacijama bilo je 82,8% primarnih promena i 68,4% recidiva. U odnosu na pol, primarnih je bilo kod 56% muškaraca i 44% žena, dok su recidivi bili češći kod žena (58,2%). Što se veličine tumora tiče, 85,3% primarnih i 72,6% recidiva imali su veličinu do 2 cm u prečniku, dok je 14,7% primarnih i 27,4% recidiva bilo veće od 2 cm u prečniku. Kompletna ekscizija predstavlja osnovu hirurškog lečenja bazocelularnog karcinoma kože. Dobijeni rezultati mogu biti koristan vodič u lečenju i praćenju bazocelularnog karcinoma kože.
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