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2017, vol. 56, iss. 3, pp. 137-142
Demographic characteristics of basal cell carcinoma: A retrospective study of 1884 lesions
aUniveristy of Niš, Faculty of Medicine + Clinical Centre Niš, Clinic of Plastic and Reconstructive Surgery
bClinical Centre Niš, Clinic of Plastic and Reconstructive Surgery
cPharmaceutical company 'Pharma Swiss', Niš
dDental practice 'Your dentist', Aleksinac

emailgste66@yahoo.com
Abstract
Basal cell carcinoma represents one of the most frequent skin cancers, accounting for around 75% of all skin cancers. Numerous etiological factors contribute to its development (from the genetics to sun exposure). To present the demographic characteristics and distribution of basal cell carcinoma and to evaluate the topography of lesions and their correlations with gender, age, location, size and recurrence rate. This retrospective study included 1734 patients with 1884 lesions, treated at the Clinic of Plastic and Reconstructive Surgery at the Clinical Center Niš, from January 2012 to December 2016. The following parameters were evaluated: age, gender, location, size, histologic type, margin of excision and recurrence rate. Out of the total of 1884 tumors, there were 1621 primary and 263 recurrent cases. High risk localizations included 82.8% of primary and 68.4% of recurrent tumors. With respect to gender, primary tumors were present in 56% of men and 44% of women, while recurrent tumors were present in 41.8% of men and 58.2% of women. Concerning the tumor size, 85.3% of primary and 72.6% of recurrent tumors had a maximum of 2 cm in diameter, whereas 14.7% of primary and 27.4% of recurrent tumors had a diameter of over 2 cm. Complete excision represents a key surgical treatment of basal cell skin cancer. The obtained algorithm can be a useful guide for the monitoring and surgical treatment of basal cell skin cancer.
References
Ad Hoc Task Force, Connolly, S.M., Baker, D.R., Coldiron, B.M., Fazio, M.J., Storrs, P.A., i dr. (2012) AAD/ACMS/ ASDSA/ASMS2012 appropriate use criteria for mohs micrographic surgery: A report of the American Academy of Dermatology, American College of Mohs Surgery, American Society for Dermatologic Surgery Association, and the American Society for Mo. J Am Acad Dermatol, 67(4), 531-50
Bariani, R.L., Nahas, F.X., Barbosa, M.V.J., Farah, A.B., Ferreira, L.M. (2006) Basal cell carcinoma: an updated epidemiological and therapeutically profile of an urban population. Acta Cirurgica Brasileira, 21(2): 66-73
Batra, R. S. (2002) Predictors of Extensive Subclinical Spread in Nonmelanoma Skin Cancer Treated With Mohs Micrographic Surgery. Archives of Dermatology, 138(8): 1043
Chen, J.G., Fleischer, A.B., Smith, E.D., Kancler, C., Goldman, N.D., Williford, P.M., Feldman, S.R. (2001) Cost of Nonmelanoma Skin Cancer Treatment in the United States. Dermatologic Surgery, 27(12): 1035-1038
Christenson, L.J. (2005) Incidence of Basal Cell and Squamous Cell Carcinomas in a Population Younger Than 40 Years. JAMA, 294(6): 681
Cigna, E., Tarallo, M., Maruccia, M., Sorvillo, V., Pollastrini, A., Scuderi, N. (2011) Basal Cell Carcinoma: 10 Years of Experience. Journal of Skin Cancer, 2011: 1-5
Conway, R.M. (2004) Surgery for primary basal cell carcinoma including the eyelid margins with intraoperative frozen section control: comparative interventional study with a minimum clinical follow up of 5 years. British Journal of Ophthalmology, 88(2): 236-238
Diepgen, T.L., Mahler, V. (2002) The epidemiology of skin cancer. Br J Dermatol, 146 Suppl 61: 1-6
Fleischer, A.B., Feldman, S.R., Barlow, J.O., Zheng, B., Hahn, H.B., Chuang, T., Draft, K.S., Golitz, L.E., Wu, E., Katz, A.S., Maize, J.C., Knapp, T., Leshin, B. (2001) The specialty of the treating physician affects the likelihood of tumor-free resection margins for basal cell carcinoma: Results from a multi-institutional retrospective study. Journal of the American Academy of Dermatology, 44(2): 224-230
Gulleth, Y., Goldberg, N., Silverman, R.P., Gastman, B.R. (2010) What Is the Best Surgical Margin for a Basal Cell Carcinoma: A Meta-Analysis of the Literature. Plastic and Reconstructive Surgery, 126(4): 1222-1231
Huang, C.C., Boyce, S.M. (2004) Surgical margins of excision for basal cell carcinoma and squamous cell carcinoma. Seminars in Cutaneous Medicine and Surgery, 23(3): 167-173
Khandwala, M.A., Lalchan, S., Chang, B.Y. P., Habib, M., Chakrabarty, A., Cassells-Brown, A. (2005) Outcome of Periocular Basal Cell Carcinoma Managed by Overnight Paraffin Section. Orbit, 24(4): 243-247
Kyrgidis, A., Vahtsevanos, K., Tzellos, T.G., Xirou, P., Kitikidou, K., Antoniades, K., i dr. (2010) Clinical histological and demographic predictors for recurrence and second primary tumours of head and neck basal cell carcinoma. A 1062 patient-cohort study from a tertiary cancer referral hospital. Eur J Dermatol, 20: 276-82
Luz, F.B., Ferron, C., Cardoso, G.P. (2016) Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma. Anais Brasileiros de Dermatologia, 91(6): 726-731
Mainz, J. (2003) Defining and classifying clinical indicators for quality improvement. International Journal for Quality in Health Care, 15(6): 523-530
Mosterd, K., Krekels, G.A.M., Nieman, F.H.M., Ostertag, J.U., Essers, B.A.B., Dirksen, C.D., Steijlen, P.M., Vermeulen, A., Neumann, H.A.M., Kelleners-Smeets, N.W.J. (2008) Surgical excision versus Mohs' micrographic surgery for primary and recurrent basal-cell carcinoma of the face: a prospective randomised controlled trial with 5-years' follow-up. Lancet Oncology, 9(12): 1149-1156
Nagore, E., Grau, C., Molinero, J., Fortea, J.M. (2003) Positive margins in basal cell carcinoma: Relationship to clinical features and recurrence risk. A retrospective study of 248 patients. J Eur Acad Dermatol Venereol, 17(2): 167-70
Pichardo-Velazquez, P., Dominguez-Cherit, J., Vega-Memije, M., Moreno-Coutino, G., Proy, H. (2004) Surgical option for nonmelanoma skin cancer. Int J Dermatol, 43(2): 148-50
Rowe, D.E., Carroll, R.J., Day, C.L. (2013) Long-Term Recurrence Rates in Previously Untreated (Primary) Basal Cell Carcinoma: Implications for Patient Follow-Up. Journal of Dermatologic Surgery and Oncology, 15(3): 315-328
Rowe, D.E., Carroll, R.J., Day, C.L. (2013) Mohs Surgery Is the Treatment of Choice for Recurrent (Previously Treated) Basal Cell Carcinoma. Journal of Dermatologic Surgery and Oncology, 15(4): 424-431
Sherry, K.R., Reid, L.A., Wilmshurst, A.D. (2010) A five year review of basal cell carcinoma excisions. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63(9): 1485-1489
Telfer, N.R., Colver, G.B., Morton, C.A. (2008) Guidelines for the management of basal cell carcinoma. British journal of dermatology, 159(1): 35-48
Thomas, D.J., King, A.R., Peat, B.G. (2003) Excision Margins for Nonmelanotic Skin Cancer. Plastic and Reconstructive Surgery, 112(1): 57-63
Trakatelli, M., Ulrich, C., Marmol, V., Euvrard, S., Euvard, S., Stockfleth, E., Abeni, D. (2007) Epidemiology of nonmelanoma skin cancer (NMSC) in Europe: Accurate and comparable data are needed for effective public health monitoring and interventions. British journal of dermatology, 156 Suppl 3: 1-7
Wetzig, T., Woitek, M., Eichhorn, K., Simon, J.C., Paasch, U. (2010) Surgical Excision of Basal Cell Carcinoma with Complete Margin Control: Outcome at 5-Year Follow-Up. Dermatology, 220(4): 363-369
Wong, V.A., Marshall, J.A., Whitehead, K.J., Williamson, R.M., Sullivan, T.J. (2002) Management of Periocular Basal Cell Carcinoma With Modified En Face Frozen Section Controlled Excision. Ophthalmic Plastic & Reconstructive Surgery, 18(6): 430-435
 

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article language: English
document type: Original Scientific Paper
DOI: 10.5633/amm.2017.0321
published in SCIndeks: 15/03/2018
Creative Commons License 4.0