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2020, vol. 77, br. 7, str. 758-761
Listeria monocytogenes multifokalni cerebritis kod imunokompetentnog bolesnika
aUniverzitet u Beogradu, Medicinski fakultet + Klinički centar Srbije, Klinika za infektivne i tropske bolesti, Beograd
bKlinički centar Srbije, Služba za mikrobilogiju, Beograd

e-adresamijovan@eunet.rs
Ključne reči: meningitis, listeria; infekcija, listerija; antibiotici, kombinovani; kotrimoksazol; tomografija
Sažetak
Uvod. Multifokalni cerebritis koji uzrokuje Listeria monocytogenes je retko i teško oboljenje koje je u literaturi opisano samo u nekoliko slučajeva. Prikaz bolesnika. Bolesnik star 64 godine primljen je u bolnicu poremećene svesti (Glasgow Coma Scale skor: 9) nakon 16 dana prethodne febrilnosti, glavobolje i bola u desnom uvu. Nije imao drugih prethodnih bolesti, niti je bio imunokompromitovan. Dobijen je podatak o alergiji na penicilin. Pri neurološkom pregledu nisu evidentirani meningealni znaci i fokalni neurološki poremećaji, a snimak endokranijuma kompjuterizovanom tomografijom sa kontrastom pokazao je tri hipodenzne zone u okcipitalnom i jednu u desnom temporalnom lobusu. Laboratorijski nalazi u krvi i cerebrospinalnoj tečnosti upućivali su na infektivnu prirodu promena u endokranijumu (multifokalni cerebritis). Incijalna terapija bila je kombinacija cefotaksima, amikacina i metronidazola, a nakon izolacije L. monocytogenes u kulturi cerebrospinalne tečnosti i hemokulturi, terapija je zamenjena ko-trimoksazolom. Oporavak stanja svesti sa uspostavljanjem budno-svesnog stanja nastupio je nakon šest dana od primene ko-trimoksazola. Ukupno trajanje terapije ko-trimoksazolom iznosilo je 36 dana. U tom periodu normalizovali su se svi klinički i laboratorijski parametri. Bolesnik je otpušten kao oporavljen, sa sekvelama amnezije i usporenog govora. Zaključak. U lečenju multifokalnog cerebritisa uzrokovanog L. monocytogenes neophodan je adekvatan izbor i dugotrajna primena antibiotske terapije. Lek izbora je ampicilin, ali u slučaju alergije na njega, ko-trimoksazol predstavlja dobru zamenu.
Reference
Aladro, Y., Ponce, P., Santullano, V., Angel-Moreno, A., Santana, M. A. (1996) Cerebritis due to Listeria monocytogeneses: CT and Mr findings. European Radiology, 6(2): 188-188
Al-Khatti, A.A., Al-Tawfiq, J.A. (2010) Listeria monocytogenes brain abscess in a patient with multiple myeloma. Journal of Infection in Developing Countries, 4(12): 849-851
Antal, E., Løberg, E.M., Bracht, P., Melby, K.K., Maehlen, J. (2001) Evidence for intraaxonal spread of Listeria monocytogenes from the periphery to the central nervous system. Brain Pathology, 11(4): 432-438
Beach, J.E., Perrott, J., Turgeon, R.D., Ensom, M.H.H. (2017) Penetration of vancomycin into the cerebrospinal fluid: A systematic review. Clinical Pharmacokinetics, 56(12): 1479-1490
Charlier, C., Perrodeau, É., Leclercq, A., Cazenave, B., Pilmis, B., Henry, B., et al. (2017) Clinical features and prognostic factors of listeriosis: The MONALISA national prospective cohort study. Lancet Infect Dis, 17(5): 510-519
Cone, L.A., Leung, M.M., Byrd, R.G., Annunziata, G.M., Lam, R.Y., Herman, B.K. (2003) Multiple cerebral abscesses because of Listeria monocytogenes: Three case reports and a literature review of supratentorial Listerial brain abscess(es). Surgical Neurology, 59(4): 320-328
Dee, R.R., Lorber, B. (1986) Brain abscess due to Listeria monocytogenes: Case report and literature review. Clinical Infectious Diseases, 8(6): 968-977
Duncan, J.M. (1989) Listeria and psychiatric syndromes. British Journal of Psychiatry, 154(6): 887-887
Haykal, H., Zamani, A., Wang, A., Barsotti, J. (1987) CT features of early Listeria monocytogenes cerebritis. Am J Neuroradiol (AJNR), 8(2): 279-82
Join-Lambert, O.F., Ezine, S., le Monnier, A., Jaubert, F., Okabe, M., Berche, P., Kayal, S. (2005) Listeria monocytogenes-infected bone marrow myeloid cells promote bacterial invasion of the central nervous system. Cellular Microbiology, 7(2): 167-180
Kellner, M., Sonntag, A., Strian, F. (1990) Psychiatric sequelae of listeriosis. British Journal of Psychiatry, 157(2): 299-299
Lorber, B. (1997) Listeriosis. Clin Infect Dis, 24(1): 1-9; quiz 10-1
Marget, W., Sellinger, H.P.R. (1988) Listeria monocytogenes infections: Therapeutic possibilities and problems. Infection, 16(Suppl 2): S175-S177
Merle-Melet, M., Dossou-Gbete, L., Maurer, P., Meyer, P., Lozniewski, A., Kuntzburger, O., et al. (1996) Is amoxicillin-cotrimoxazole the most appropriate antibiotic regimen for listeria meningoencephalitis?: Review of 22 cases and the literature. J Infect, 33(2): 79-85
Michelet, C., Leib, S.L., Bentue-Ferrer, D., Täuber, M.G. (1999) Comparative efficacies of antibiotics in a rat model of meningoencephalitis due to Listeria monocytogenes. Antimicrobial Agents and Chemotherapy, 43(7): 1651-1656
Mylonakis, E., Hohmann, E.L., Calderwood, S.B. (1998) Central nervous system infection with Listeria monocytogenes: 33 Years' experience at a general hospital and review of 776 episodes from the literature. Medicine, Baltimore, 77(5): 313-336
Nielsen, H., Gyldensted, C., Harmsen, A. (1982) Cerebral abscess: Aetiology and pathogenesis, symptoms, diagnosis and treatment: A review of 200 cases from 1935-1976. Acta Neurol Scand, 65(6): 609-22
Pagliano, P., Arslan, F., Ascione, T. (2017) Epidemiology and treatment of the commonest form of listeriosis: Meningitis and bacteraemia. Infez Med, 25(3): 210-216
Patel, K., Clifford, D.B. (2014) Bacterial brain abscess. Neurohospitalist, 4(4): 196-204
Polat, M., Kara, S.S., Tapısız, A., Derinöz, O., Çağlar, K., Tezer, H. (2016) Successful treatment of refractory listeria meningitis and bacteremia with trimethoprim-sulfamethoxazole in an immunocompetent child. Turkish Journal of Pediatrics, 58(2): 220-222
Reynaud, L., Graf, M., Gentile, I., Cerini, R., Ciampi, R., Noce, S., Gentile, F., Borrelli, F., Viola, C., Briganti, F., Borgia, G. (2007) A rare case of brainstem encephalitis by Listeria monocytogenes with isolated mesencephalic localization: Case report and review. Diagnostic Microbiology and Infectious Disease, 58(1): 121-123
Rouquette, C., Berche, P. (1996) The pathogenesis of infection by Listeria monocytogenes. Microbiologia, 12(2): 245-58
Salata, R.A., King, R.E., Gose, F., Pearson, R.D. (1986) Listeria monocytogenes cerebritis, bacteremia, and cutaneous lesions complicating hairy cell leukemia. American Journal of Medicine, 81(6): 1068-1072
Seeliger, H. (1955) Listeriose. u: Habs H; Kathe J. [ur.] Beiträge zur Hygiene und Epidemiologie, Leipzig: Barth JA Verlag
Spitzer, P.G., Hammer, S.M., Karchmer, A.W. (1986) Treatment of Listeria monocytogenes infection with trimethoprim-sulfamethoxazole: Case report and review of the literature. Clinical Infectious Diseases, 8(3): 427-430
Temple, M.E., Nahata, M.C. (2000) Treatment of Listeriosis. Annals of Pharmacotherapy, 34(5): 656-661
Wacker, P., Ozsahin, H., Groll, A.H., Gervaix, A., Reinhard, L., Humbert, J. (2000) Trimethoprim-sulfamethoxazole salvage for refractory listeriosis during maintenance chemotherapy for acute lymphoblastic leukemia. Journal of Pediatric Hematology/Oncology, 22(4): 340-343
Watson, G.W., Fuller, T.J., Elms, J., Kluge, R.M. (1978) Listeria cerebritis: Relapse of infection in renal transplant patients. Arch Intern Med, 138(1): 83-7