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2020, vol. 148, br. 11-12, str. 727-731
Promene debljine sloja ganglijskih ćelija i unutrašnjeg pleksiformnog sloja kod bolesnika sa senilnom degeneracijom žute mrlje
aUniverzitet u Nišu, Medicinski fakultet, Katedra Otorinolaringologija i oftalmologija + Klinički centar Niš, Klinika za očne bolesti
bUniverzitet u Beogradu, Medicinski fakultet, Katedra Oftalmologija
cKlinički centar Niš, Klinika za očne bolesti
dOčna klinika "Dr Sefić", Sarajevo, Federacija Bosne i Hercegovine, Bosna i Hercegovina
eDom zdravlja Niš, Niš
fSpecijalna bolnica za oftalmologiju "Klinika Maja", Niš
gUniverzitet u Kragujevcu, Fakultet medicinskih nauka, Katedra za otorinolaringologiju i oftalmologiju

e-adresadrsvetlanajovanovic@yahoo.com
Ključne reči: suva SDM; vlažna SDM; sloj ganglijskih ćelija; kompleks ganglijskih ćelija
Sažetak
Uvod/Cilj Cilj studije je bio da se analiziraju promene debljine sloja ganglijskih ćelija i unutrašnjeg pleksiformnog sloja SGĆ + UPS kod bolesnika sa suvim i vlažnim oblikom senilne degeneracije makule (SDM) u odnosu na kontrolnu grupu. Metod Studija je sprovedena na 195 bolesnika sa SDM i 94 zdrave osobe (srednja starosna dob 75,2 ± 7,8 godina; opseg 55-86 godina). Bolesnici su podeljeni u tri grupe: grupa I - 100 bolesnika sa vlažnom SDM, II grupa - 95 bolesnika sa suvom SDM i kontrolna grupa III - 94 ispitanika bez sistemskih ili očnih bolesti. Ispitivanje je vršeno pomoću Cirrus SD-OCT (Carl Zeiss Meditec, Inc., Dablin, Kalifornija, SAD). Merene su prosečna debljina makule, kao i prosečna i minimalna debljina SGĆ + UPS i debljina SGĆ + UPS u svih šest sektora. Statistička analiza izvršena je korišćenjem SPSS verzije 20.0 primenom odgovarajućih statističkih metoda. Vrednost r < 0,05 se smatrala statistički značajnim rezultatom. Rezultati Prosečna debljina SGĆ + UPS kod bolesnika sa vlažnom formom SDM iznosila je 43,13 mm, kod bolesnika sa suvom SDM bila je 66,73 mm, a u kontrolnoj grupi 86,23 mm. Prosečne vrednosti SGĆ + UPS i vrednosti minimalne debljine SGĆ + UPS statistički ce značajno razlikuju između grupa (p < 0,001) i bile su tanje u vlažnoj formi SDM (p < 0,001) nego kod suve forme SDM. U grupi suve forme SDM, prosečna debljina SGĆ + UPS i minimalna debljina SGĆ + UPS su statistički tanje nego kod zdravih ocoba (p < 0,001). Zaključak SDM odlikuje istanjenje SGĆ + UPS. Bolesnici sa vlažnom formom SDM imaju tanji SGĆ + UPS u poređenju sa bolesnicima sa suvom formom SDM.
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O članku

jezik rada: engleski
vrsta rada: originalan članak
DOI: 10.2298/SARH181226097Z
primljen: 26.12.2018.
revidiran: 28.09.2020.
prihvaćen: 21.10.2020.
objavljen onlajn: 29.10.2020.
objavljen u SCIndeksu: 06.01.2021.

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