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Srpski arhiv za celokupno lekarstvo
2022, vol. 150, br. 9-10, str. 585-588
Intratekalna terapija baklofenom i infekcija kovidom 19 - prikaz tri bolesnika
Nikolić Igora, Nestorović Dragoslavb ORCID, Repac Nikolaa, Knežević Sašac, Tasić Gorana
aUniverzitet u Beogradu, Medicinski fakultet, Srbija + Klinički centar Srbije, Klinika za neurohirurgiju, Beograd, Srbija
bKlinički centar Srbije, Centar za radiologiju i magnetnu rezonancu, Beograd, Srbija
cKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, Beograd, Srbija

e-adresa: i.m.nikolic@gmail.com
Ključne reči: intratekalna terapija; baklofen; spasticitet; kovid 19
Sažetak
Uvod Bolesnici sa teškim spasticitetom efikasno se leče intratekalnom terapijom baklofenom. Zbog njihove invalidnosti, u slučaju infekcije prognoza je loša. Prikaz bolesnika Predstavljamo tri bolesnika (dva muškarca i jednu ženu) lečena intratekalnom terapijom baklofenom zbog izraženog spasticiteta sva četiri ekstremiteta koji su preležali infekciju virusom SARS-CoV2. Dva bolesnika imaju multiplu sklerozu, a jedan traumu cervikalnog segmenta kičmene moždine. Sva tri bolesnika razvila su kliničku sliku infekcije kovidom 19 unutar šest meseci od ugradnje pumpe za intratekalnu terapiju baklofenom. Lečeni su u bolničkim uslovima sa nepromenjenom dozom leka, bez pogoršanja neurološkog statusa. Bartelov indeks i modifikovani Rankin skor bili su isti pre i posle infekcije kovidom 19. U dva slučaja Bartelov indeks je bio 20, a u jednom 69, a modifikovani Rankin skor bio je 3 u jednom slučaju i 5 u dva slučaja. Zaključak Bolesnici sa teškim stepenom spasticiteta, kod kojih je neophodna intratekalna terapija baklofenom, mogu se bezbedno lečiti bez obzira na pandemiju kovida 19.
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O članku

jezik rada: engleski
vrsta rada: prikaz slučaja
DOI: 10.2298/SARH211222076N
primljen: 22.12.2021.
revidiran: 07.07.2022.
prihvaćen: 19.07.2022.
objavljen onlajn: 21.07.2022.
objavljen u SCIndeksu: 04.11.2022.
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