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2019, vol. 72, iss. 5-6, pp. 165-170
Application of the eighth edition of the American Joint Committee on Cancer staging system for oral carcinoma
University of Novi Sad, Faculty of Medicine + Clinical Centre of Vojvodina, Clinic for Maxillofacial Surgery, Novi Sad
Introduction. Oral squamous cell carcinoma is the sixth most common carcinoma in the world. Annually, it accounts for 5% of all newly discovered cancers. The most important prognostic factor is the stage of the disease. The tumor, node, and metastasis staging system has been the cornerstone for clinical classification of oral squamous cell carcinoma. Material and Methods. The study included 65 patients with oral squamous cell carcinoma who underwent surgery at the Clinic of Maxillofacial Surgery of the Clinical Center of Vojvodina in Novi Sad. The tumor, node, and metastasis status was determined according to 7th and 8th edition of the tumor, node, and metastasis classification. Results. Statistical differences between the 7th and 8th edition of tumor, node, and metastasis classification were examined. There was also a change in the nodal status; in 20% of patients there was a transition from N1 to N2, as a result of a more precise definition of nodal status in patients with oral carcinoma. Conclusion. This research has pointed out the significance of tumor size as a predictive factor in oral squamous cell carcinoma, which indicates the importance of its local control (for surgical and radiological treatment). The 8th edition of the tumor, node, and metastasis classification for oral cavity cancers made a significant shift by clearly defining depth of tumor invasion into the tumor status.
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article language: English
document type: Professional Paper
DOI: 10.2298/MPNS1906165M
published in SCIndeks: 03/06/2020