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2016, vol. 55, br. 3, str. 76-84
Fitoterapijski pristup tretmanu benigne hiperplazije prostate semenom bundeve (Cucurbita pepo L., Cucurbitaceae)
aUniverzitet u Nišu, Medicinski fakultet, Katedra Patologija
bUniverzitet u Nišu, Medicinski fakultet, Katedra Farmacija
cUniverzitet u Nišu, Medicinski fakultet, Stomatološka klinika
dUniverzitet u Nišu, Medicinski fakultet

e-adresaivanadjordjevic01.12@gmail.com
Projekat:
Tradicionalni i novi proizvodi od plodova gajenih i samoniklih vrsta voćaka i vinove loze i nus-produkata u preradi, sa posebnim osvrtom na autohtone sorte: hemijska karakterizacija i biološki profil (MPNTR - 46013)
Preventivni, terapijski i etički pristup prekliničkim i kliničkim istraživanjima gena i modulatora redoks ćelijske signalizacije u imunskom, inflamatornom i proliferativnom odgovoru ćelije (MPNTR - 41018)

Ključne reči: benigna hiperplazija prostate; simptomi donjeg urinarnog trakta muškaraca; seme bundeve; fitoterapija
Sažetak
Benigna hiperplazija prostate (BPH) je nekancerozno uvećanje prostate izazvano proliferacijom stromalnih i epitelnih ćelija. Razvija se nakon četrdesete godine života i ima visoku stopu morbiditeta i nisku stopu mortaliteta. Simptomi donjeg urinarnog trakta kod muškaraca (LUTS) su uglavnom povezani sa BPH i veoma su česti u starijoj populaciji. Biljni lekovi se koriste za lečenje brojnih hroničnih i teških bolesti. Glavni cilj fitoterapije u benignoj hiperplaziji prostate je da ublaži simptome i poboljša kvalitet života bolesnika (QoL). Bundeva (Cucurbita pepo L.), član porodice Cucurbitaceae, je zeljasta, jednodomna, jednogodišnja biljka. Ekstrakti iz različitih delova bundeve su pokazali različite terapijske efekte zbog svojih biološki aktivnih komponenti. Seme bundeve je korisno zbog visoke koncentracije proteina, esencijalnih aminokiselina, masnih kiselina i mikro elemenata. Seme bundeve je pokazalo pozitivne rezultate u terapiji blagih urinarnih poremećaja, bolesti prostate i mokraćne bešike. Terapija sintetičkim lekovima i hirurške procedure daju mnoge neželjene efekte i komplikacije, tako da su biljni lekovi obećavajući u blagim i umerenim formama BPH.
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O članku

jezik rada: engleski
vrsta rada: pregledni članak
DOI: 10.5633/amm.2016.0310
objavljen u SCIndeksu: 21.01.2017.
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