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2017, vol. 4, br. 3, str. 559-567
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Znanje i stavovi studenata farmacije u vezi sa upotrebom kanabisa u medicinske svrhe
Pharmacy students’ knowledge and attitudes regarding cannabis for medical purposes
aUniverzitet u Novom Sadu, Medicinski fakultet, Zavod za farmakologiju, toksikologiju i kliničku farmakologiju bZavod za laboratorijsku dijagnostiku, Medlab, Novi Sad
e-adresa: olga.horvat@mf.uns.ac.rs
Projekat: Interakcije ksenobiotika i uticaj na sisteme u biomedicini (MPNTR - 41012)
Sažetak
Uvod: Kako je poslednjih godina u Srbiji sve veće interesovanje javnosti za legalizacijom kanabisa u terapijske svrhe, farmaceuti često bivaju konsultovani o bezbednosti, efikasnosti kanabisa i njegovih pripravaka. Zbog toga je cilj naše studije bio odrediti znanje i stavove studenata farmacije o upotrebi kanabisa i njegovih pripravaka u terapijske svrhe u Srbiji kako bi se uvidelo da li je potrebno poboljšati edukaciju o toj temi. Metodologija: Istraživanje je sprovedeno na slučajnom uzorku od 80 studenata završne godine studije farmacije Medicinskog fakulteta u Novom Sadu. Studenti su bili zamoljeni da popune anonimni upitnik koji bi pokazao njihovo znanje i stavove o upotrebi kanabisa i njegovih pripravaka u terapijsk svrhe. Svi ispitanici su pre popunjavanja upitnika dobili informacije o ispitivanju, pročitali informacije za ispitanike i potpisali informisani pristanak. Istraživanje je sprovedeno u periodu od 1.8.2017 do 15.8.2017. i odobreno je od strane Komisije za etičnost kliničkih ispitivanja, Medicinskog fakulteta u Novom Sadu. Upitnik se sastojao od tri grupe izjava sa kojima su studenti bili zamoljeni da označe stepen slaganja, ako jesu se odnosile na znanje studenata o upotrebi kanabisa i njegovih pripravaka u terapijske svrhe, potencijalnim negativnim efektima, izdavanju u apoteci i legalizaciji kanabisa i njegovih pripravak u terapijske svrhe. Rezultati: Iako se 91, 2% ispitanika složilo da kanabis i njegovi pripravci potencijalno mogu imati terapijski efekat, znatno niži procenat ispitanika (51,3%) bio je upoznat sa mogućim terapijskim dejstvima kanabisa. Isti procenat ispitanika edukovao se o tome, osim na fakultetu, i na dodatnim edukacijama. Oko 30% smatralo je da upotreba kanabisa i njegovih pripravaka u terapijske svrhe potencijalno može izazvati njihovu zloupotrebu, a sličan procenat ispitanika (33, 8%) smatrao je da izdavanje kanabisa i njegovih pripravaka u apoteci može izložiti farmaceuta određenim opasnostima kao sto su insistiranje na bezreceptnom izdavanju ili pljačka. Oko 90 % ispitanika složilo se da su neophodne jasne smernice za upotrebu kanabisa i njegovih pripravaka u terapijske svrhe, a 76, 3% ispitanika smatralo je da je za njihovo izdavanje neophodan lekarski recept. Većina ispitanika (75%) složilo se da bi, na osnovu iskustava drugih država, upotreba kanabisa u medicinske svrhe trebala biti odobrena i u Srbiji. Zaključak: Većina studenata farmacije je podržala upotrebu kanabisa u terapijske svrhe, ali smatrajući da bi to trebalo biti praćeno striktnim zakonskim regulativama i jasno određenim smernicama. Neophodna je potpunija edukacija studenata farmacije o terapijskim efektima kanabisa.
Abstract
Introduction: With the growing trend for legalization of cannabis and its derivatives in Serbia, pharmacists are likely to be consulted on the safety, efficacy, and drug-drug or drug-disease interactions of medical cannabis. Thus, the aim of our study was to assess pharmacy students’ knowledge and attitude toward medical cannabis use in Serbia to determine if additional education is needed. Subjects and methods: In the study students from the final year of the study program of integrated academic studies of pharmacy at the Faculty of Medicine, University of Novi Sad were asked to complete an anonymous questionnaire regarding their knowledge and attitudes on the use of cannabis and its derivatives in medical purposes. After giving their written informed consent, they were instructed by the researchers on how to complete the questionnaire. All questionnaires were administered between August 1, 2017 and August 15, 2017. The study was approved by the Ethical Committee of the Faculty of Medicine in Novi Sad; a total of 80 questionnaires were distributed. The questionnaire consisted of 3 groups of statements on which they should mark level of their agreement related to students’ knowledge about the use of cannabis and its derivatives in therapeutical purposes, potential negative effects, dispensing in a pharmacy and legalization of cannabis and its derivatives in medical purposes. Results: Although 91.2% of the respondents agreed that cannabis and its derivatives could potentially have therapeutical effects, much lower percentage of respondents (51.3%) were familiar with possible therapeutical effects of cannabis. The same percentage of respondents learned about therapeutical effects of cannabis from sources other than school. About third (31.3%) of our respondents thought that the use of cannabis and its derivatives in therapeutical purposes could cause their abuse and the similar percentage of respondents (33.8%) thought that issuing cannabis and its derivatives in the pharmacy could expose a pharmacist to the certain dangers such as insisting on the issuing without the prescription or robbery. About 90% of the respondents agreed it is necessary to create clear guidelines for the use of cannabis and its derivatives in therapeutical purposes and 76.3% of the respondents thought that doctor’s prescription is necessary for their dispensing in a pharmacy. Most of the respondents (75%) agreed that, based on the experiences of the countries which have approved the use of cannabis and its derivatives in therapeutical purposes, its use in those purposes should be approved in Serbia. Conclusion: The majority of pharmacy students supported medical cannabis legalization but only with strict legal regulations and clear guidelines for their use implemented. Further education of the pharmacist about therapeutical effect of cannabis is necessary.
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Reference
|
|
|
*** (1929) Criminal code of the Kingdom of Serbs, Croats and Slovenes. Belgrade: Državna štamparija, pp. 70-71
|
|
  
|
Aggarwal, S.K., Carter, M.M.G.T., Sullivan, M.D., ZumBrunnen, C., Morrill, R., Mayer, J.D. (2018) Medicinal use of cannabis in the United States: Historical perspectives, current trends, and future directions. Journal of Opioid Management, 5(3): 153
|
|
|
Balkan Insight (2015) Croatia legalizes marijuana for medical use. http://www.balkaninsight.com/en/article/croatia-firstbalkan-county-to-legalize-medical-marijuana-10-15-2015-1, October 23 2015
|
|
|
Beal, J.E., Olson, R., Laubenstein, L., Morales, J.O., Bellman, P., Yangco, B., Lefkowitz, L., Plasse, T.F., Shepard, K.V. (1995) Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS. Journal of Pain and Symptom Management, 10(2): 89-97
|
|
|
Ben, A.M. (2006) Cannabinoids in medicine: A review of their therapeutic potential. Journal of ethnopharmacology, 105(1-2): 1-25
|
|
|
Berenji, J., Martinov, M. (1997) Hemp in Yugoslavia: Past, present and future. u: 2. Biorohstoff Hanf, Frankfurt am Main, Proceedings, 91-101
|
|
|
Bifulco, M., Pisanti, S. (2015) Medicinal use of cannabis in Europe: The fact that more countries legalize the medicinal use of cannabis should not become an argument for unfettered and uncontrolled use. EMBO reports, 16(2): 130-132
|
|
|
Burke, W.M., Marx, M.B. (1971) Attitudes of Professional Students toward Legal Control of Psychoactive Substances. HSMHA Health Reports, 86(8): 725
|
|
|
Chesher, G.B., Jackson, D.M. (1985) The quasi-morphine withdrawal syndrome: Effect of cannabinol, cannabidiol and tetrahydrocannabinol. Pharmacology Biochemistry and Behavior, 23(1): 13-15
|
|
|
Cunha, J.M., Carlini, E.A., Pereira, A.E., Ramos, O.L., Pimentel, C., Gagliardi, R., Sanvito, W.L., Lander, N., Mechoulam, R. (1980) Chronic administration of cannabidiol to healthy volunteers and epileptic patients. Pharmacology, 21(3): 175-85
|
|
|
European Monitoring Centre for Drugs and Drug Addiction (2017) Cannabis legislation in Europe: An overview. Luxembourg: Publications Office of the European Union
|
|
|
European Monitoring Centre for Drugs and Drug Addiction (2017) Cannabis legislation in Europe: An overview. Luxembourg: Publications Office of the European Union
|
|
|
Guy, G., Whittle, B.A., Robson, P.J. (2004) Medical Uses of Cannabis and Cannabinoids. London: Pharmaceutical Press
|
|
1
|
Hall, W., Solowij, N., Lemon, J. (1994) The Health and Social Consequences of Cannabis Use. u: Monograph Series No. 25, Canberra: Australian Government Publishing Service
|
|
|
Haney, M., Gunderson, E.W., Rabkin, J., Hart, C.L., Vosburg, S.K., Comer, S.D., Foltin, R.W. (2007) Dronabinol and Marijuana in HIV-Positive Marijuana Smokers. JAIDS Journal of Acquired Immune Deficiency Syndromes, 45(5): 545-554
|
|
|
Hollister, L.E. (1986) Health aspects of cannabis. Pharmacological reviews, 38(1): 1-20
|
|
|
Jain, A.K., Ryan, J.R., Mcmahon, F. G., Smith, G. (2013) Evaluation of Intramuscular Levonantradol and Placebo in Acute Postoperative Pain. Journal of Clinical Pharmacology, 21(S1): 320S-326S
|
|
|
Johansson, R., Kilkku, P., Groenroos, M. (1982) A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy. Cancer Treatment Reviews, 9: 25-33
|
|
|
Mallat, A., Roberson, J., Brock-Utne, J.G. (1996) Preoperative marijuana inhalation--an airway concern. Canadian Journal of Anesthesia / Journal canadien d'anesthésie, 43(7): 691-3
|
|
|
Merritt, J.C., Crawford, W.J., Alexander, P.C., Anduze, A.L., Gelbart, S.S. (1980) Effect of marihuana on intraocular and blood pressure in glaucoma. Ophthalmology, 87(3): 222-8
|
|
|
Moeller, K.E., Woods, B. (2015) Pharmacy Students' Knowledge and Attitudes Regarding Medical Marijuana. American Journal of Pharmaceutical Education, 79(6): 85
|
|
|
Neziri, H. (2015) use of marijuana for therapeutic purposes: Pro i contra. Zagreb, Diploma Thesis
|
|
|
Pertwee, R.G. (1991) Tolerance to and dependence on psychotropic cannabinoids. u: Pratt J.A. [ur.] The Biological Bases of Drug Tolerance and Dependence, London: Academic Press, 231-63
|
|
|
Petro, D.J. (1980) Marihuana as a therapeutic agent for muscle spasm or spasticity. Psychosomatics, 21(1): 81, 85
|
|
1
|
Tomida, I., Azuara-Blanco, A., House, H., Flint, M., Pertwee, R.G., Robson, P.J. (2006) Effect of sublingual application of cannabinoids on intraocular pressure: a pilot study. Journal of glaucoma, 15(5): 349-53
|
|
|
United Nations Office on Drugs and Crime (2014) The illicit drug trade through South-Eastern Europe. United Nations publication, March
|
|
|
United Nations Office on Drugs and Crime (2015) World drug report 2015. u: United Nations publication, Sales No. E.15.XI.6
|
|
|
United Patients Group Ways to consume medical cannabis. http://www.unitedpatientsgroup.com/resources/methods-of-consumption, (October 23, 2017)
|
|
|
Vujčić, I., Pavlović, A., Dubljanin, E., Maksimović, J., Nikolić, A., Sipetić-Grujicić, S. (2017) Attitudes Toward Medical Cannabis Legalization Among Serbian Medical Students. Subst Use Misuse, 52(9): 1225-31; doi: 10.1080/10826084.2017.1302959
|
|
1
|
Wilsey, B., Marcotte, T., Tsodikov, A., Millman, J., Bentley, H., Gouaux, B., Fishman, S. (2008) A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain. journal of pain, 9(6): 506-21
|
|
|
Zhan, G., Camras, C.B., Palmberg, P.F., Toris, C.B. (2005) Effects of marijuana on aqueous humor dynamics in a glaucoma patient. Journal of glaucoma, 14(2): 175-7
|
|
1
|
Zuardi, A.W. (2006) History of cannabis as a medicine: a review. Revista Brasileira de Psiquiatria, 28(2): 153-157
|
|
|
|
|