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2013, vol. 47, br. 2, str. 80-84
Epidemiološki aspekti glijalnih tumora
aUniverzitet u Beogradu, Medicinski fakultet, KBC 'Zemun'
bKlinički centar Kragujevac, Klinika za psihijatriju

e-adresadrnzivkovic@yahoo.com
Ključne reči: neoplazije mozga; glioma; faktori rizika
Sažetak
Glijalni tumori su najčešći primarni tumori mozga. Većina glijalnih tumora je maligna, a 80% od njih čine glioblastomi. Incidenca glijalnih tumora mozga veća je u razvijenim zemljama zapadne Evrope, Severne Amerike, Australije i Novog Zelanda. U Srbiji, maligni tumori mozga čine 2,2% od svih tumora. Glijalni tumori su češći kod muškaraca. Srednje preživljavanje pacijenata sa glioblastomima je između 12 i 24 meseca. Do danas, veoma malo se zna o faktorima rizika za nastajanje ovih tumora. Visoke doze terapijskog jonizujućeg zračenja su jedini ustanovljen faktor rizika koji utiče na nastanak glijalnih tumora, meningioma i tumora nervnih omotača. Dve nedavno publikovane studije o povezanosti glioma i promena na genima, otkrile su i verifikovale pet hromozomskih regija u kojima postoji rizik za nastanak glijalnih tumora. Bolje razumevanje geneze ovih tumora dovelo bi do napretka u lečenju i eventualnom boljem ishodu pacijenata sa ovom teškom dijagnozom.
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O članku

jezik rada: srpski
vrsta rada: prikaz
DOI: 10.5937/mckg47-1889
objavljen u SCIndeksu: 20.05.2013.

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