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Journal of Medical Biochemistry
2015, vol. 34, iss. 2, pp. 228-232
Laryngeal granuloma: Benefit in treatment with zinc supplementation?
Đukić Vojkoa, Krejović-Trivić Sanjaa, Vukašinović Milana, Trivić Aleksandara, Pavlović Bojana, Milovanović Aleksandarb, Milovanović Jovicaa ORCID
aClinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
bUniversity of Belgrade, Faculty of Medicine, Institute of Occupational Health 'Dr Dragomir Karajović', Serbia

email: drskt@sbb.rs
Keywords: conservative treatment; laryngeal granuloma; zinc supplementation
Abstract
Laryngeal granulomas present as contact and postintubation ulcers and granulomas. Essentially, a contact granuloma is a pseudotumor of the lateral wall of the posterior glottis. The most common etiological factor is voice abuse, with predisponing factors such as reflux disease. Postintubation ulcers and granulomas, although of different etiology, according to all the other traits belong to this clinical entity. The therapy of choice is conservative treatment. Surgical laser excision is indicated for resistant cases and those whose size is causing respiratory distress. Treatment of laryngeal granulomas with zinc supplementation is reported in the literature as one of the forms of conservative treatment, and we wanted to consider it in this review. Zinc is an essential mineral that plays a vital role in many biochemical reactions and is considered very important for wound healing.
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About

article language: English
document type: Professional Paper
PMC ID: PMC4922326
DOI: 10.2478/jomb-2014-0028
published in SCIndeks: 03/01/2020

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