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2020, iss. 40, pp. 62-65
Antifungal activity of the essential oil from Artemisia santonicum and its constituent isogeranic acid
aUniversity of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM, Serbia
bUniversity of Belgrade, Faculty of Chemistry, Serbia
cUniversity of Belgrade, Institute for Biological Research 'Siniša Stanković', Serbia
dInstitute for Medicinal Plant Research 'Dr. Josif Pančić ', Belgrade, Serbia
eUniversity of Belgrade, Faculty of Agriculture, Serbia
Ministry of Education, Science and Technological Development, Republic of Serbia (Institution: University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) (MESTD - 451-03-68/2020-14/200026)

Keywords: antifungal activity; essential oil; isogeranic acid
This study represents a continuation of exploring of the biological activities of the Artemisia santonicum essential oil. The previous investigation was focused on the antibacterial, antibiofilm, and antiquorum activities of A. santonicum essential oil and isogeranic acid as the main antibacterial constituent. The present study describes its antifungal activity. The antifungal activity of the A. santonicum essential oil was tested against eight fungi isolates, whereas antifungal effects of isogeranic acid were studied using four fungi species, because of the limited quantities of the isolated compound. The results were compared to the commercial antimycotics, bifonazole and ketoconazole. Antifungal activity of isogeranic acid against all tested fungi was significantly higher in comparison to the essential oil and the both controls.
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article language: English
document type: Research
DOI: 10.5937/leksir2040062S
received: 05/05/2020
accepted: 16/12/2020
published online: 20/12/2020
published: 25/12/2020
published in SCIndeks: 31/12/2020
Creative Commons License 4.0

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