Metrics

  • citations in SCIndeks: 0
  • citations in CrossRef:0
  • citations in Google Scholar:[]
  • visits in previous 30 days:4
  • full-text downloads in 30 days:2

Contents

article: 3 from 7  
Back back to result list
Medicinski pregled
2014, vol. 67, iss. 5-6, pp. 154-160
Comparative analysis of success of psoriasis treatment with standard therapeutic modalities and balneotherapy
Ninković-Baroš Đukaa, Gajanin Vesna S.b, Gajanin Radoslav B.a, Zrnić Bogdanb
aUniversity Clinical Centre of the Republic of Srpska, Banja Luka, Republic of Srpska, B&H
bUniversity of Banja Luka, Faculty of Medicine, Republic of Srpska, B&H
Abstract
Introduction. Psoriasis is a chronic, inflammatory, immune-mediated skin disease. In addition to standard therapeutic modalities (antibiotics, cytostatics, phototherapy, photochemotherapy and retinoids), nonstandard methods can be used in the treatment of psoriasis. This includes balneotherapy which is most commonly used in combination with therapeutic resources. The aim of this research was to determine the length of remission of psoriasis in patients treated with standard therapeutic modalities, balneotherapy, and combined treatment (standard therapeutic modalities and balneotherapy). Material and Methods. The study analyzed 60 adult patients, of both sexes, with different clinical forms of psoriasis, who were divided into three groups according to the applied therapeutic modalities: the first group (treated with standard therapeutic modalities), the second group (treated with balneotherapy) and the third group (treated with combined therapystandard methods therapy and balneotherapy). The Psoriasis Area and Severity Index was determined in first, third and sixth week of treatment for all patients. The following laboratory analysis were performed and monitored: C reactive protein, iron with total iron binding capacity, unsaturated iron binding capacity and ferritin, uric acid, rheumatoid factors and antibodies to streptolysin O in the first and sixth week of treatment. Results. The average length of remission in patients treated with standard therapeutic modalities and in those treated with balneotherapy was 1.77 ± 0.951 months and 1.79 ± 0.918 months, respectively. There was a statistically significant difference in the duration of remission between the patients treated with combination therapy and patients treated with standard therapeutic modalities (p=0.019) and balneotherapy (p=0.032). Conclusion. The best results have been achieved when the combination therapy was administered.
References

Belić, D., Ristić-Nikolić, S., Damjan, S., Ratkov, I., Čeke, M. (2004) Heredity of psoriasis. Medicinski pregled, vol. 57, br. 3-4, str. 171-174

Blasco, A.J., Lázaro, P., Ferrándiz, C., García-Díez, A., Liso, J. (2009) Efficiency of biologic agents in the treatment of moderate to severe psoriasis. Actas dermo-sifiliográficas, 100(9): 792-803

1

Brockow, T., Schiener, R., Franke, A., Resch, K.L., Peter, R.U. (2007) A pragmatic randomized controlled trial on the effectiveness of highly concentrated saline spa water baths followed by UVB compared to UVB only in moderate to severe psoriasis. Journal of alternative and complementary medicine (New York, N.Y.), 13(7): 725-32

Carlin, C.S., Feldman, S.R., Krueger, J.G., Menter, A., Krueger, G.G. (2004) A 50% reduction in the Psoriasis Area and Severity Index (PASI 50) is a clinically significant endpoint in the assessment of psoriasis. Journal of the American Academy of Dermatology, 50(6): 859-66

1

Chodorowska, G., Wojnowska, D., Juszkiewicz-Borowiec, M. (2004) C-reactive protein and alpha2-macroglobulin plasma activity in medium-severe and severe psoriasis. Journal of the European Academy of Dermatology and Venereology, 18(2): 180-3

Coimbra, S., Oliveira, H., Reis, F., Belo, L., Rocha, S., Quintanilha, A., Figueiredo, A., Teixeira, F., Castro, E., Rocha-Pereira, P., Santos-Silva, A. (2010) C-reactive protein and leucocyte activation in psoriasis vulgaris according to severity and therapy. Journal of the European Academy of Dermatology and Venereology, 24(7): 789-96

Colombo, D., Cassano, N., Altomare, G., Giannetti, A., Vena, G.A. (2010) Psoriasis relapse evalution with week-end cyclosporine a treatment: results of a randdomized, double-blind, multicentric study. Int J Immunopathol Pharmacol, 23(4): 1143-1152

Eisen, A.Z., Seegmiller, J.E. (1961) Uric acid metabolism in psoriasis. Journal of clinical investigation, 40: 1486-94

Eysteinsdóttir, J.H., Ólafsson, J.H., Agnarsson, B.A., Lúðvíksson, B.R., Sigurgeirsson, B. (2014) Psoriasis treatment: faster and long-standing results after bathing in geothermal seawater. A randomized trial of three UVB phototherapy regimens. Photodermatology, photoimmunology & photomedicine, 30(1): 25-34

2

Falagas, M.E., Zarkadoulia, E., Rafailidis, P.I. (2009) The therapeutic effect of balneotherapy: evaluation of the evidence from randomised controlled trials. International journal of clinical practice, 63(7): 1068-84

Feldman, S.R., Yentzer, B.A. (2009) Topical clobetasol propionate in the treatment of psoriasis: a review of newer formulations. American journal of clinical dermatology, 10(6): 397-406

Ghosh, A., Mukhopadhyay, S., Kar, M. (2008) Role of free reactive iron in psoriasis. Indian journal of dermatology, venereology and leprology, 74(3): 277-8

Gonzalez-Gay, M.A., Gonzalez-Juanatey, C., Vazquez-Rodriguez, T.R., Gomez-Acebo, I., Miranda-Filloy, J.A., Paz-Carreira, J., Martin, J., Llorca, J. (2009) Asymptomatic hyperuricemia and serum uric acid concentration correlate with subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease. Seminars in arthritis and rheumatism, 39(3): 157-62

1

Griffiths, C.E.M., Barker, J.N.W.N. (2007) Pathogenesis and clinical features of psoriasis. Lancet, 370(9583): 263-71

Gudjonsson, J.E., Thorarinsson, A.M., Sigurgeirsson, B., Kristinsson, K.G., Valdimarsson, H. (2003) Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study. British journal of dermatology, 149(3): 530-4

Halverstam, C.P., Lebwohl, M. (2008) Nonstandard and off-label therapies for psoriasis. Clinics in dermatology, 26(5): 546-53

Islam, M.T., Paul, H.K., Zakaria, S.M., Islam, M.M., Shafiquzzaman, M. (2011) Epidemiological determinants of psoriasis. Mymensingh medical journal, 20(1): 9-15

Kalb, R.E., Strober, B., Weinstein, G., Lebwohl, M. (2009) Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference. Journal of the American Academy of Dermatology, 60(5): 824-37

Karadaglić, Đ. (2000) Dermatologija. in: Karadaglić Đ. [ed.] Beograd: Vojnoizdavački zavod / VIZ

Katz, K.A. (2005) Psoriasis Area and Severity Index 50 as an endpoint in psoriasis trials: an unconvincing proposal. Journal of the American Academy of Dermatology, 53(3): 547-51

1

Kazandjieva, J., Grozdev, I., Darlenski, R., Tsankov, N. (2008) Climatotherapy of psoriasis. Clinics in dermatology, 26(5): 477-85

Lapolla, W., Yentzer, B.A., Bagel, J., Halvorson, C.R., Feldman, S.R. (2011) A review of phototherapy protocols for psoriasis treatment. Journal of the American Academy of Dermatology, 64(5): 936-49

Lebwohl, M. (2003) Psoriasis. The Lancet, 361(9364): 1197-1204

Leslie, K.S., Millington, G.W.M., Levell, N.J. (2004) Sulphur and skin: from Satan to Saddam!. Journal of cosmetic dermatology, 3(2): 94-8

Louden, B., Pearce, D.J., Lang, W., Feldman, S.R. (2004) A Simplified Psoriasis Area Severity Index (SPASI) for rating psoriasis severity in clinic patients. Dermatology online journal, 10(2): 7

1

Meier, M., Sheth, P.B. (2009) Clinical spectrum and severity of psoriasis. Current problems in dermatology, 38: 1-20

Nasermoaddeli, A., Kagamimori, S. (2005) Balneotherapy in medicine: A review. Environmental Health and Preventive Medicine, 10(4): 171-179

Pariser, D.M., Bagel, J., Gelfand, J.M., Korman, N.J., Ritchlin, C.T., Strober, B.E., van Voorhees, A.S., Young, M., Rittenberg, S., Lebwohl, M.G., Horn, E.J. (2007) National Psoriasis Foundation clinical consensus on disease severity. Archives of dermatology, 143(2): 239-42

Peroni, A., Gisondi, P., Zanoni, M., Girolomoni, G. (2008) Balneotherapy for chronic plaque psoriasis at Comano spa in Trentino, Italy. Dermatologic Therapy, 21: S31-S38

2

Poljački, M.N., Begenešić, M., Đuran, V.D., Matović, L., Matić, M., Jovanović, M., Stojanović, S., Roš, T. (2002) Psorijaza i oboljenja kože autoimunske prirode. Medicinski pregled, vol. 55, br. 7-8, str. 325-328

Prinz, J.C. (2009) The role of streptococci in psoriasis. Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete, 60(2): 109-15

Roos, S., Hammes, S., Ockenfels, H.M. (2010) Psoriasis. Natural versus artificial balneophototherapy. Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete, 61(8): 683-90

Sabat, R., Philipp, S., Höflich, C., Kreutzer, S., Wallace, E., Asadullah, K., Volk, H., Sterry, W., Wolk, K. (2007) Immunopathogenesis of psoriasis. Experimental dermatology, 16(10): 779-98

1

Schiffner, R., Schiffner-Rohe, J., Wölfl, G., Landthaler, M., Glässl, A., Walther, T., Hofstädter, F., Stolz, W. (2000) Evaluation of a multicentre study of synchronous application of narrowband ultraviolet B phototherapy (TL-01) and bathing in Dead Sea salt solution for psoriasis vulgaris. British journal of dermatology, 142(4): 740-7

Smith, C.H., Barker, J.N.W.N. (2006) Psoriasis and its management. BMJ (Clinical research ed.), 333(7564): 380-4

Sutton, B., Corper, A., Bonagura, V., Taussig, M. (2000) The structure and origin of rheumatoid factors. Immunology today, 21(4): 177-83

van de Kerkhof, P.C.M. (2001) Therapeutic strategies: rotational therapy and combinations. Clinical and Experimental Dermatology, 26(4): 356-361

Weedon, D., ur. (2002) David Weedon skin pathology. London: Churchill Livingstone
   

About

article language: English
document type: Original Scientific Paper
DOI: 10.2298/MPNS1406154N
published in SCIndeks: 09/05/2014

Related records

Medicinski pregled (2012)
Evaluation of effect of local administration of desoximetasone and ditranol in psoriatic lesion by applying 20MHz ultrasound
Stojković Tatjana, et al.

Vojnosanitetski pregled (2015)
Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis
Golušin Zoran, et al.

Medicinski pregled (2010)
Fibromyalgia: Up to date aspects of patophysiology, diagnosis and treatment
Tomašević-Todorović Snežana, et al.

show all [6]