Metrics

  • citations in SCIndeks: [1]
  • citations in CrossRef:0
  • citations in Google Scholar:[]
  • visits in previous 30 days:19
  • full-text downloads in 30 days:14

Contents

article: 8 from 17  
Back back to result list
2014, vol. 67, iss. 3-4, pp. 97-99
Diagnosis of neurosarcoidosis: Necessity of biopsy
aClinical Center of Serbia, Clinic for Pulmonology, Belgrade
bClinical Center of Serbia, Clinic for Pulmonology, Belgrade + University of Belgrade, Faculty of Medicine
cClinical Center of Serbia, Clinic for Neurology, Belgrade
dClinical Center of Serbia, Clinic for Psychiatry, Belgrade
Project:
Clinical and epidemiological study of adverse events in hospital patients (MESTD - 175046)
Significance of early diagnosis of obstructive sleep apnea syndrome in professional drivers operating motor vehicles (MESTD - 175081)

Abstract
Introduction: Sarcoidosis can affect any part of the central nervous system presenting with an extremely diverse clinical picture. Clinical presentations actually depend on the localization of granulomas in the central nervous system. Making diagnosis according to the localization and the clinical variations is often a clinical challenge. Diagnosis of Neurosarcoidosis. Diagnosis is based on the clinical picture, clinical and radiological findings (magnetic resonance imaging with contrast endocranium), laboratory findings (angio-tenzin-converting enzyme and chitotriosidase in cerebrospinal fluid); however, it is necessary first to exclude all other possible causes of granulomatous inflammation. Recent studies in patients with neurosarcoidosis show a high value of at least one marker of the disease. The safest way and the gold standard in diagnosing this disease would be histopathological confirmation, which is rarely performed due to its invasiveness. Conclusion. New diagnostic methods will contribute to better methods of bypassing invasive procedures, and they will significantly facilitate the diagnosis of neurosarcoidosis, which is a real challenge even for experienced clinicians who deal with this disease.
References
Filipović, S., Mihailović-Vučinić, V., Omčikus, M., Videnović-Ivanov, J., Stjepanović, M., Šumarac, Z. (2013) Hitotriozidaza-potencijalni biomarker u sarkoidozi. Med Pregl, Suppl 1, u štampi
Judson, M.A., Baughman, R.P., Teirstein, A.S., Terrin, M.L., Yeager, H. (1999) Defining organ involvement in sarcoidosis: the ACCESS proposed instrument. ACCESS Research Group. A Case Control Etiologic Study of Sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis, 16(1): 75-86
Judson, M.A., Baughman, R.P., Thompson, B.W., Teirstein, A.S., Terrin, M.L., Rossman, M.D., Yeager, H., McLennan, G., Bresnitz, E.A., DePalo, L., Hunninghake, G., Iannuzzi, M.C. (2003) Two year prognosis of sarcoidosis: the ACCESS experience. Sarcoidosis Vasc Diffuse Lung Dis, 20(3): 204-11
Khoury, J., Wellik, K.E., Demaerschalk, B.M., Wingerchuk, D.M. (2009) Cerebrospinal fluid angiotensin-converting enzyme for diagnosis of central nervous system sarcoidosis. Neurologist, 15(2): 108-11
Marangoni, S., Argentiero, V., Tavolato, B. (2006) Neurosarcoidosis. Clinical description of 7 cases with a proposal for a new diagnostic strategy. J Neurol, 253(4): 488-95
Mumović, G., Mitrović, M.S., Veselinović, M. (2008) Arbutina a potential new marker of sarcoidosis severity. Respiration, 76(2): 234-238
Savić, M., Stjepanović, M., Mihailović-Vučinić, V., Gvozdenović, B., Filipović, S., Mujović, N. (2013) Sarkoidoza-novine u dijagnostici. Med Pregl, 66(suppl. 1): 22-25
Stjepanović, M., Mihailović-Vučinić, V., Mijajlovic, M., Videnović-Ivanov, J., Filipović, S., Omčikus, M., i dr. (2013) Dijagnostika neurosarkoidoze, novine i naša iskustva. Journal of the Association of pulmologists from Republic of Srpska, 3(1-2): 18
Stjepanović, M., Mihailović-Vučinić, V., Dudvarski-Ilić, A., Videnović-Ivanov, J., Škodrić-Trifunović, V., Popević, S. (2013) Kliničke manifestacije neurosarkoidoze. Med Pregl, 66(suppl. 1): 54-59
Stjepanović, M. (2013) Vanplućne komplikacije plućne sarkoidoze-neurosarkoidoza: evaluacija, terapija i komplikacije zahvaćenosti nervnog sistema. Beograd: Medicinski fakultet, Univerzitet u Beogradu, Akademski specijalistički rad
Škodrić-Trifunović, V., Vučinić, V., Simić-Ogrizović, S., Stević, R., Stjepanović, M., Ilić, K., Savić, Ž. (2012) Mystery called sarcoidosis: Forty-four years follow-up of chronic systemic disease. Srpski arhiv za celokupno lekarstvo, vol. 140, br. 11-12, str. 768-771
Terushkin, V., Stern, B.J., Judson, M.A., Hagiwara, M., Pramanik, B., Sanchez, M., Prystowsky, S. (2010) Neurosarcoidosis: presentations and management. Neurologist, 16(1): 2-15
Zajicek, J.P., Scolding, N.J., Foster, O., Rovaris, M., Evanson, J., Moseley, I.F., Scadding, J.W., Thompson, E.J., Chamoun, V., Miller, D.H., McDonald, W.I., Mitchell, D. (1999) Central nervous system sarcoidosis: diagnosis and management. QJM, 92(2): 103-17
 

About

article language: English
document type: Review Paper
DOI: 10.2298/MPNS1404097S
published in SCIndeks: 11/04/2014

Related records

Medicinski pregled (2014)
Radiological presentation of neurosarcoidosis
Stjepanović Mihailo I., et al.

Medicinski pregled (2014)
Treatment of neurosarcoidosis: Innovations and challenges
Stjepanović Mihailo I., et al.

Srps arh celokup lekarstvo (2021)
Neurosarcoidosis: An ever-present clinical challenge
Stjepanović Mihailo, et al.