Metrika

  • citati u SCIndeksu: 0
  • citati u CrossRef-u:0
  • citati u Google Scholaru:[]
  • posete u poslednjih 30 dana:7
  • preuzimanja u poslednjih 30 dana:6

Sadržaj

članak: 1 od 28  
Back povratak na rezultate
2021, vol. 71, br. 3, str. 207-223
Efekat imunizacije vakcinom protiv gripa na prirodna antitela
Centar za imunološka istraživanja 'Branislav Janković' Torlak, Beograd

e-adresaizivkovic@torlak.rs
Projekat:
Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije (institucija: Centar za imunološka istraživanja 'Branislav Janković' Torlak, Beograd) (MPNTR - 451-03-68/2020-14/200177)

Ključne reči: prirodna antitela; imunizacija; imunološka homeostaza
Sažetak
Prirodna, polireaktivna i slabo afinitetna antitela igraju važnu ulogu ne samo u neposrednoj odbrani od patogena, već i u oblikovanju stečenog imunskog odgovora. S druge strane, indukcija visoko afinitetnih, antigen - specifičnih antitela, može uticati na ravnotežu prirodnih antitela i time dovesti do autoimunskih bolesti. U ovoj studiji analizirali smo da li imunizacija ljudi split ili celovirusnom vakcinom protiv gripa može dovesti do promena u IgM i IgG pulu prirodnih antitela. Za analizu su korišćeni "in-house" razvijeni ELISA testovi. Ispitanici su podeljeni prema vakcinalnom statusu na one koji su prethodnih godina bili imunizovani vakcinom protiv gripa i one koji su prvi put imunizovani. Pokazano je da imunizacijom nije narušen ukupan pul prirodnih antitela ni u jednoj grupi i da je došlo do određenih fluktuacija u nivoima prirodnih antitela kako bi se održala homeostaza imunskog sistema.
Reference
Novododat članak: provera, normiranje i linkovanje referenci u toku.
Reyneveld IJ, Savelkoul H, Parmentier H. Current Understanding of Natural Antibodies and Exploring the Possibilities of Modulation Using Veterinary Models: A Review. Front Immunol. doi: 10.3389/fimmu.2020.02139
Besredka M. Les antihemolysines naturelles. Ann Inst Pasteur. 1901;15:758 -63
Katz J, Parikh K. Intravenous Immunoglobulin: Medscape [Internet]. [updated Jul 05, 2018; cited 2021 Apr 03]. Available from: https://emedicine.medscape.com/article/210367-overview#a3
Zivkovic I, Minic R, Dimitrijevic L. Antimicrobial Immunoglobulin Prophylaxis and Therapy. In: Atta-ur-Rahman, editor. Frontiers in Clinical Drug Research: Anti Infectives 6. Bentham Science Publishers eBooks, Sharjah, United Arab Emirates; 2020; p. 165-205
Avrameas S. Natural autoantibodies: from 'horror autotoxicus' to 'gnothi seauton'. Immunol Today. 1991;12(5):154-9
Cohen IR. Autoantibody repertoires, natural biomarkers, and system controllers. Trends in Immunol. 2013;34(12):620-5
Lacroix-Desmazes S, Mouthon L, Kaveri SV, Kazatchkine MD, Weksler ME. Stability of Natural Self-Reactive Antibody Repertoires During Aging. J Clin Immunol. 1999;19(1):26-34
Lacroix-Desmazes S, Kaveri SV, Mouthon L, Ayouba A, Malanchere E, Coutinho A, Kazatchkine MD. Self-reactive antibodies natural autoantibodies in healthy individuals. J Immunol Methods. 1998;216(1-2):117-37
Palma J, Tokarz-Deptuła B, Deptuła J, Deptuła W. Natural antibodies - facts known and unknown. Centr Eur J Immunol. 2018;43(4):466-75
Baumgarth N, Tung JW, Herzenberg LA.Inherent specificities in natural antibodies: A key to immune defense against pathogen invasion. Springer Semin Immunopathol. 2005;26(4):347-62
Jerne NK. Towards a network theory of the immune system. Ann Immunol. (Inst. Pasteur) 1974;125C:373-89
Adib M, Ragimbeau J, Avrameas S, Ternynck T. IgG autoantibody activity in normal mouse serum is controlled by IgM. J. Immunol. 1990;145(11):3807-13
Zivkovic I, Petrusic V, Dimitrijevic R, Stojanovic M, Dimitrijevic Lj. Adjuvant dependence of APS pathology-related low-affinity antibodies during secondary immune response to tetanus toxoid in BALB/c mice. Immunol Res. 2013;56(1):143-9
Petrusic V, Todorovic N, Zivkovic I, Dimitrijevic R, Muhandes L, Rajnpreht I, Dimitrijevic L. Autoantibody response and pregnancy-related pathology induced by combined LPS and tetanus toxoid hyperimmunization inBALB/c and C57BL/6 mice. Autoimmunity. 2014;48(2):87-99
Petrusic V, Zivkovic I, Muhandes L, Dimitrijevic R, Stojanovic M, Dimitrijevic L. Infection-induced autoantibodies and pregnancy related pathology: an animal model. Reprod Fertil Dev. 2014;26(4):578-86
Zivkovic I, Stojanovic M, Petrusic V, Inic-Kanada A, Dimitrijevic L. Induction of APS after TTd hyper-immunization has a different outcome in BALB/c and C57BL/6 mice. Am J Reprod Immunol. 2011;65:492-502
Zivkovic I, Petrusic V, Stojanovic M, Inic-Kanada A, Stojicevic I, Dimitrijevic L. Induction of decreased fecundity by tetanus toxoid hyper-immunization in C57BL/6 mice depends on the applied adjuvant. Innate Immun. 2012;18(2):333-42
Stäger S, Alexander J, Kirby AC, Botto M, Rooijen NV, Smith DF, Brombacher F, Kaye PM. Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses. Nat Med. 2003;9(10):1287-92
Haury M, Sundblad A, Grandien A, Barreau C, Coutihno A, Nobrega A. The repertoire of serum IgM in normal mice is largely independent of external antigenic contact. Eur J Immunol. 1997;27:1557-63
Masmoudi H, Mota-Santos T, Huetz F, Coutinho A, Cazenave PA. All T15 Id-positive antibodies (but not the majority of VHT15+ antibodies) are produced by peritoneal CD5+ B lymphocytes. Int Immunol. 1990;2(6):515-20
Baumgarth N, Herman OC, Jager GC, Brown LE, Herzenberg LA, Chen J. B-1 and B-2 Cell-derived Immunoglobulin M Antibodies Are Nonredundant Components of the Protective Response to Influenza Virus Infection, J Exp Med. 2000;192(2):271-80
Harada Y, Muramatsu M, Shibata T, Honjo T, Kuroda K. Unmutated immunoglobulin M can protect mice from death by influenza virus infection. J Exp Med. 2003;197:1779-85
Jayasekera JP, Moseman EA, Carroll MC. Natural antibody and complement mediate neutralization of influenza virus in the absence of prior immunity. J Virol. 2007;81(7):3487-94
Kaveri S, Silverman G, Bayry J. Natural IgM in immune equilibrium and harnessing their therapeutic potential. J Immunol. 2012;188(3):939-45
Gonzalez FS, Jayasekera JP, Carroll MC. Complement and natural antibody are required in the longterm memory response to influenza virus. Vaccine. 2008;(265):186-93
Choi YS, Baumgarth N. Dual role for B-1a cells in immunity to infl uenza virus infection. J Exp Med. 2008;205(13):3053-64
Yang L, Myers JL, Bostick DL, Sullivan CB, Madara J, Linderman SL, Liu Q, Carter DM, Wrammert J, Esposito S, Principi N, Plotkin JB, Ross TM, Ahmed R, Wilson PC, Hensley SE. Immune history shapes specificity of pandemic H1N1 influenza antibody responses. J Exp Med. 2013;210(8):1493-500
Avrameas S, Ternynck T, Tsonis IA, Lymberi P. Naturally occurring B-cell autoreactivity: A critical overview. J Autoimmun. 2007;29:213-8
Dimitrijevic LA, Stojanovic M, Ciric B, Radulovic M, Stojanovic R, Popovic Z, Inic-Kanada A, Zivkovic I. Expression of Y7 Cross-Reactive Idiotopeon Human IgM Molecules. Immunol Invest. 2004;33(1):1-14
Petrusic V, Zivkovic I, Stojanovic M, Stojicevic I, Marinkovic E, Inic-Kanada A, Dimitrijevic L. Antigenic specificity and expression of a natural idiotope on human pentameric and hexameric IgM polymers. Immunol Res. 2011;51:97-107
Dimitrijevic LA, Radulovic MI, Ciric BP, Petricevic MM, Inic AB, Nikolic DN, Apostolski S. Human monoclonal IgM DJ binds to ssDNA and human commensal bacteria. Hum Antibodies. 1999;9:37-45
Radulovic, M., Ciric, B., Jurisic, A., Jankov, R., Apostolski, S., Zivancevic-Simonovic, S., Dimitrijevic, L. Expression of Y7 idiotope on IgM molecules from cord sera. In: Lukic M, Mostarica-Stojkovic M, Cuperlovic K, Colic M, editors. Immune Regulation in Health and Disease. London: Acad. Press Ltd; 1997; p. 205-11
Dimitrijevic L, Radulovic M, Ciric B, Odrljin T, Jankov RM, Marzari R. Immunochemical characterisation of a murinemonoclonal anti-idiotypic antibody. J Immunoassay. 1992;13:181-96
Francis TJ. On the doctrine of original antigenic sin. Proc. Am. Philos. Soc. 1960;104(6):572-8
Vatti A, Monsalve D, Pacheco Y, Chang C, Anaya JM, Gershwin ME. Original antigenic sin: A comprehensive review. J Autoimmun. 2017;83:12-21
Lafond KE, Porter RM, Whaley MJ, Suizan Z, Ran Z, Aleem MA et al. Global Respiratory Hospitalizations-Influenza Proportion Positive (GRIPP) Working Group. Global burden of influenza-associated lower respiratory tract infections and hospitalizations among adults: A systematic review and meta-analysis. PLoS Med. 2021;1;18(3):e1003550
Zschaler J, Schlorke D, Arnhold J. Differences in innate immune response between man and mouse. Crit Rev Immunol. 2014;34(5):433-54
Grönwall C, Vas J, Silverman GJ. Protective roles of natural IgM antibodies. Front Immunol. 2012;3:66
Avrameas S. Autopolyreactivity Confers a Holistic Role in the Immune System. Scand J Immunol. 2016;83(4):227-34
Poletaev A, Osipenko L. General network of natural autoantibodies as immunological homunculus (Immunculus). Autoimmun Rev. 2003;2(5):264-71
Sinyakov MS, Avtalion RR. Vaccines and natural antibodies: A link to be considered. Vaccine. 2009;27:1985-6
Beinart D, Ren D, Pi C, Poulton S, Holzknecht ZE, Swanson C et al. Immunization enhances the natural antibody repertoire. EXCLI J. 2017;16:1018-30
Sabbaga J, Pankewycz O, Lufft V, Schwartz R, Madaio M. Cross-reactivity Distinguishes Serum and Nephritogenic Anti-DNA Antibodies in Human Lupus from their Natural Counterparts in Normal Serum. J Autoimmun. 1990;3(2):215-35
McIntyre JA, Wagenknecht DR, Faulk WP. Antiphospholipid antibodies: discovery, definitions, detection and disease. Prog Lipid Res. 2003;42(3):176-237
Lardone RD, Yuki N, Odaka M, Daniotti JL, Irazoqui FJ, Nores GA. Anti-GM1 IgG antibodies in Guillain-Barré syndrome: fine specificity is associated with disease severity. J Neurol Neurosurg Psychiatry. 2010;81(6):629-33
Cats EA, Jacobs BC, Yuki N, Tio-Gillen AP, Piepers S, Franssen H et al. Multifocal motor neuropathy: association of anti-GM1 IgM antibodies with clinical features. Neurology 2010;75(22):1961-7
van Schaik IN, Bossuyt PM, Brand A, Vermeulen M. Diagnostic value of GM1 antibodies in motor neuron disorders and neuropathies: a meta-analysis. Neurology 1995;45(8):1570-7
Galili U. Anti-Gal: an abundant human natural antibody of multiple pathogeneses and clinical benefits. Immunology. 2013;140(1):1-11
Abdel-Motal UM, Guay HM, Wigglesworth K, Welsh RM, Galili U. Increased immunogenicity of influenza virus vaccine by anti-Gal mediated targeting to antigen pre-senting cells. J Virol. 2007;81:9131-41
 

O članku

jezik rada: engleski
vrsta rada: izvorni naučni članak
DOI: 10.5937/arhfarm71-31544
objavljen u SCIndeksu: 12.06.2021.
metod recenzije: jednostruko anoniman
Creative Commons License 4.0

Povezani članci

Nema povezanih članaka