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Serbian Journal of Anesthesia and Intensive Therapy
2013, vol. 35, br. 3-4, str. 127-134
Evaluacija i interpretacija različitih biomarkera kod kritično obolelih pacijenata
Janković Radmiloa, Savić Nenadb, Sokolović Dušanc ORCID, Budić Ivanad, Sabljak Verae, Marković Dejanf
aKlinički centar Niš, Centar za anesteziologiju i reanimaciju, Srbija
bKlinički centar Niš, Klinika za opštu hirurgiju, Srbija
cUniverzitet u Nišu, Medicinski fakultet, Institut za biohemiju, Srbija
dKlinički centar Niš, Klinika za dečju hirurgiju i ortpopediju, Srbija
eKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, Beograd, Srbija
fKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, Beograd, Srbija + Univerzitet u Beogradu, Medicinski fakultet, Srbija

e-adresa: jankovic.radmilo@gmail.com
Ključne reči: biomarkeri; sepsa; disfunkcija organa; genomika; savremene tehnologije
Sažetak
Upotreba biomarkera omogućava novi pristup u tretmanu kritično obolelih pacijenata. Tokom poslednje decenije uloženo je mnogo napora u identifikaciju i kliničku primenu idealnih biomarkera. Zaista, danas su različiti biomarkeri moćno dijagnostičko i prognostičko sredstvo za tretman sepse ili poremećaja funkcije određenih organa kao: akutni koronarni sindrom, srčana slabost, akutni respiratorni distres sindrom, akutna bubrežna slabost ili moždani udar. Ipak, za razumnu i sigurnu primenu biomarkera u kliničkoj praksi moraju da budu prepoznate kako snaga tako i slabosti svakog od njih. Od istraživačke metode, genomika se danas pretvorila u klinički primenljivu, donoseći novu eru u dijagnostikovanju različitih stanja kritično obolelih. Još uvek je otvoreno pitanje kako učiniti ove tehnologije komercijalno dostupnim i razumljivim kliničarima koji bi ih koristili.
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O članku

jezik rada: srpski
vrsta rada: neklasifikovan
objavljen u SCIndeksu: 02.09.2013.

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