• citations in SCIndeks: 0
  • citations in CrossRef:0
  • citations in Google Scholar:[]
  • visits in previous 30 days:7
  • full-text downloads in 30 days:2


article: 4 from 15  
Back back to result list
2016, vol. 69, iss. 1-2, pp. 53-57
Atypical Kawasaki disease
aUniversity of Novi Sad, Faculty of Medicine, Institute for Child and Youth Health Care of Vojvodina
bUniversity of Novi Sad, Faculty of Medicine, Institute for Child and Youth Health Care of Vojvodina + University of Novi Sad, Faculty of Medicine
Introduction. Kawasaki disease is an acute vasculitis which occurs primarily in children under the age of 5. The etiology of the disease is still unknown. Diagnostic criteria for Kawasaki disease are fever and at least four of the five additional clinical signs. Incomplete Kawasaki disease should be taken into consideration in case of all children with unexplained fever for more than 5 days, associated with 2 or 3 of the main clinical findings of Kawasaki disease. The diagnosis of incomplete Kawasaki disease is based on echocardiographic findings indicating the involvement of the coronary arteries. Cardiac complications, mostly coronary artery aneurysm, can occur in 20% to 25% of untreated patients and in 4% of treated patients. Case Report. In this report we present a case of atypical Kawasaki disease in a 3.5-month-old infant. As soon as the diagnosis was made, the patient received high doses of intravenous immunoglobulin, with the initial introduction of ibuprofen, then aspirin with a good clinical response. Due to the presence of aneurysm of coronary arteries, further therapy involved aspirin and clopidogrel over the following 3 months, and then only aspirin for 2 years. There was a gradual regression of the changes in the coronary blood vessels to the normalization of the echocardiographic findings after 2 years. Conclusion. Kawasaki disease is the second most common vasculitis of childhood, so it should be included in the differential diagnosis for any child with a prolonged unexplained fever. Atypical Kawasaki disease should be taken into consideration in cases when not all clinical criteria are present but coronary abnormalities are documented.
Billoo, A.G., Lone, S.W., Siddiqui, S., Atiq, H. (2009) Incomplete Kawasaki disease: Are we missing it?. J Pak Med Assoc, 59(1): 42-3
Cox, J.R., Sallis, R.E. (2009) Recognition of Kawasaki disease. Perm J, 13(1): 57-61
Deaconu, A., Voda, D., Popovici, B., Ispas, M. (2012) Atypical Kawasaki disease case report. Bulletin of the Transilvania University of Brasov, 5(54): 105-13
Eleftheriou, D., Levin, M., Shingadia, D., Tulloh, R., Klein, N.J., Brogan, P.A. (2014) Management of Kawasaki disease. Arch Dis Child, 99(1): 74-83
Jamieson, N., Singh-Grewal, D. (2013) Kawasaki Disease: A Clinician’s Update. International Journal of Pediatrics, 2013: 1-7
Kara, A., Tezer, H., Devrim, I., Korkmaz, K.E., Karagoz, T., Ozer, S., i dr. (2006) Kawasaki disease: A case report in extreme of pediatrics. Infect Dis Pract, 14: 333-4
Kuzmanović, S., Rončević, N., Stojadinović, A. (2006) Febrilnost bez fokusa kod dece uzrasta do 36 meseci. Medicinski pregled, vol. 59, br. 3-4, str. 187-191
Lee, S.T., Nar, M.Y., Kua, K.E., Chen, W.C., Wang, N.K. (2007) Kawasaki disease presenting as cervical lymphadenitis and a retropharyngeal abscess: A case report. FJJM, 5(4): 221-6
Manlhiot, C., Yeung, R.S.M., Clarizia, N.A., Chahal, N., McCrindle, B.W. (2009) Kawasaki Disease at the Extremes of the Age Spectrum. Pediatrics, 124(3): e410-e415
Newburger, J.W. (2004) Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Associat. Circulation, 110(17): 2747-2771
Owa, J.A., Ahmad, N., Abusrair, H.A., Shawfey, S.H. (1995) Kawasaki disease: Report of three cases. Bahrain Med Bull, 17(2)
Rashid, AKM., Kamal, S., Ashrafuzzaman, Md., Mustafa, K. (2015) Kawasaki Disease and Its Treatment - An Update. Current Rheumatology Reviews, 10(2): 109-116
Tizard, E.J. (2005) Complications of Kawasaki disease. Current Paediatrics, 15(1): 62-68
Tsai, H.C., Chang, L.Y., Lu, C.Y., Shao, P.L., Fan, T.Y., Cheng, A.L., i dr. (2015) Transmission of acute infectious illness among cases of Kawasaki disease and their household members. J Formos Med Assoc, 114(1): 72-6
Williams, R.V., Minich, L.L., Tani, L.Y. (2001) Pharmacological Therapy for Patients with Kawasaki Disease. Paediatric Drugs, 3(9): 649-660
Yu, H., Lee, S., Sohn, S. (2006) Infliximab treatment for a patient with refractory Kawasaki disease. Korean Journal of Pediatrics, 49(9): 987


article language: English
document type: Case Report
DOI: 10.2298/MPNS1602053R
published in SCIndeks: 27/02/2016

Related records

No related records