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2004, vol. 61, br. 3, str. 321-325
Alergijski angiitis i granulomatoza
aVojnomedicinska akademija, Klinika za pulmologiju, Beograd
bVojnomedicinska akademija, Institut za patologiju i sudsku medicinu, Beograd
cVojnomedicinska akademija, Klinika za reumatologiju, Beograd
Sažetak
Alergijski granulomatozni angiitis (AGA) ili Churg-Straussov sindrom je retka autoimunska bolest koju karakterišu tri klinički prepoznatljive faze prodromalna, eozinofilna i vaskulitisna. Najveći broj plućnih manifestacija javlja se u prvoj i drugoj fazi bolesti. Prikazane su dve bolesnice različite starosti, čija je bolest ispunila kliničke kriterijume za dijagnozu AGA različite faze i dužine trajanja. Prva bolesnica stara 24 godine hospitalizovana je zbog pogoršanja astme, srčane slabosti i polineuropatije gornjih ekstremiteta. Druga bolesnica stara 45 godina hospitalizovana je, takođe, zbog pogoršanja astme, polineuropatije svih ekstremiteta i febrilnosti. Obe bolesnice lečene su kontinuiranom glukokortikoidnom terapijom, a starija bolesnica i intermitentnom citotoksičkom terapijom (ukupno je primenjeno šest pulsih doza ciklofosfamida). Primenom navedenih oblika lečenja postignuta je zadovoljavajuća kontrola bolesti kod obe bolesnice.
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O članku

jezik rada: srpski
vrsta rada: prikaz slučaja
DOI: 10.2298/VSP0403321T
objavljen u SCIndeksu: 02.06.2007.

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